NVIDIABlackwell

Best AI Models for NVIDIA RTX PRO 4000 Blackwell (24.0GB)

VRAM:24.0 GB GDDR7·Bandwidth:672.0 GB/s·CUDA Cores:8,960·TDP:145W·MSRP:$1,500

24 GB is the enthusiast tier for running AI models locally. It comfortably handles 7B–13B models at high quality and opens the door to larger 30B models at moderate quantization.

This is one of the most popular memory tiers for local AI, found in GPUs like the RTX 4090 and RTX 3090. You can run Llama 3 8B, Mistral 7B, and Qwen 2.5 7B at Q5_K_M or Q6_K quality with fast token generation and generous context windows. Larger 14B models like DeepSeek R1 Distill fit comfortably at Q4_K_M. For even bigger models, 30B class runs at Q2–Q3, but 70B models are generally too heavy for single-GPU inference at this tier.

Runs Well

  • 7B models (Llama 3 8B, Mistral 7B) at Q5–Q8 quality
  • 13B–14B models at Q4–Q5 quality
  • Small models (3B–4B) at FP16 precision
  • Multimodal models like LLaVA 7B

Challenging

  • 30B models only at Q2–Q3 quantization
  • 70B models do not fit in VRAM
  • Large context windows with 14B+ models

What LLMs Can NVIDIA RTX PRO 4000 Blackwell Run?

105 models · 7 excellent · 15 good

Showing compatibility for NVIDIA RTX PRO 4000 Blackwell

LLM models compatible with NVIDIA RTX PRO 4000 Blackwell — ranked by performance
ModelVRAMGrade
Q4_K_M·76.0 t/s tok/s·66K ctx·EASY RUN
5.8 GBC39
Q4_K_M·81.0 t/s tok/s·131K ctx·EASY RUN
5.4 GBC37
Qwen3 4B4.0B
Q4_K_M·150.6 t/s tok/s·41K ctx·EASY RUN
2.9 GBC31
Yi 34B Chat34.4B
Q4_K_M·20.4 t/s tok/s·4K ctx·FAIR FIT
21.4 GBB56
Q4_K_M·80.6 t/s tok/s·16K ctx·EASY RUN
5.4 GBC38
Q4_K_M·87.5 t/s tok/s·131K ctx·EASY RUN
5.0 GBC36
Hermes 3 Llama 3.1 8B8.0B
Q4_K_M·81.0 t/s tok/s·131K ctx·EASY RUN
5.4 GBC37
Q4_K_M·20.4 t/s tok/s·4K ctx·FAIR FIT
21.4 GBB56
Qwen3.6 35B A3B36.0B
Q4_K_M·19.9 t/s tok/s·262K ctx·FAIR FIT
21.9 GBB48
Q4_K_M·127.3 t/s tok/s·131K ctx·EASY RUN
3.4 GBC32
Q4_K_M·150.6 t/s tok/s·262K ctx·EASY RUN
2.9 GBC31
Yi 34B34.4B
Q4_K_M·20.4 t/s tok/s·4K ctx·FAIR FIT
21.4 GBB56
Q4_K_M·110.3 t/s tok/s·33K ctx·EASY RUN
4.0 GBC34
Yi 9B8.8B
Q4_K_M·75.3 t/s tok/s·4K ctx·EASY RUN
5.8 GBC39
Gemma 3 4B IT4.3B
Q4_K_M·153.8 t/s tok/s·EASY RUN
2.8 GBC31
Gemma 3n E2B IT5.4B
Q4_K_M·121.7 t/s tok/s·EASY RUN
3.6 GBC33

NVIDIA RTX PRO 4000 Blackwell Specifications

Brand
NVIDIA
Architecture
Blackwell
Compute Capability
12.0 (CUDA SM version)
VRAM
24.0 GB GDDR7
Memory Bandwidth
672.0 GB/s
CUDA Cores
8,960
Tensor Cores
280
TDP
145W
Release Date
2025-04-01
MSRP
$1,500

Get Started

Ollama (Recommended)

$curl -fsSL https://ollama.com/install.sh | sh
$ollama run llama3:8b

LM Studio

LM Studio

Download LM Studio, search for a model, and run it with one click.

GPUs to Consider Over NVIDIA RTX PRO 4000 Blackwell

Similar GPUs and upgrades with more VRAM or higher bandwidth for AI

Frequently Asked Questions

Can NVIDIA RTX PRO 4000 Blackwell run Qwen3.6 27B?

Yes, the NVIDIA RTX PRO 4000 Blackwell with 24 GB can run Qwen3.6 27B, Gemma 3 27B IT, Gemma 4 26B A4B IT, and 1264 other models. 69 models run at excellent quality, and 153 at good quality. Check the compatibility table above for the full list with VRAM usage and estimated speed.

Is NVIDIA RTX PRO 4000 Blackwell good for AI?

The NVIDIA RTX PRO 4000 Blackwell has 24 GB of GDDR7, making it excellent for running local AI models. It supports 222 models at good quality or better. With 672.0 GB/s memory bandwidth, it delivers solid token generation speeds. This is an enthusiast-grade GPU that handles most popular open-source LLMs.

How many parameters can NVIDIA RTX PRO 4000 Blackwell handle?

With 24 GB, the NVIDIA RTX PRO 4000 Blackwell supports models from 3B to 30B parameters depending on quantization level. At Q4_K_M (the recommended sweet spot), you can fit roughly 40B parameters. This means 7B models at high quality (Q6/Q8) or 30B+ models at Q4.

What quantization should I use on NVIDIA RTX PRO 4000 Blackwell?

For the best balance of quality and speed on the NVIDIA RTX PRO 4000 Blackwell, start with Q4_K_M — it preserves ~85% of the original model quality while keeping VRAM usage reasonable. With 24+ GB, you have the headroom to run 7B models at Q5_K_M or even Q6_K for noticeably better output quality. For larger 30B models, Q4_K_M remains the sweet spot.

How fast is NVIDIA RTX PRO 4000 Blackwell for AI inference?

With 672.0 GB/s memory bandwidth, the NVIDIA RTX PRO 4000 Blackwell achieves approximately 97 tokens/sec on a 7B model at Q4_K_M — that's very fast, well above conversational speed. A 14B model runs at ~49 tok/s. Token generation speed scales inversely with model size — smaller models are significantly faster.

tok/s = (672 GB/s ÷ model GB) × efficiency

Smaller models = faster inference. Memory bandwidth is the main bottleneck for token generation speed.

Estimated speed on NVIDIA RTX PRO 4000 Blackwell

Real-world results typically within ±20%. Speed depends on quantization kernel, batch size, and software stack.

Learn more about tok/s estimation →

What's the best model for NVIDIA RTX PRO 4000 Blackwell?

The top-rated models for the NVIDIA RTX PRO 4000 Blackwell are Qwen3.6 27B, Gemma 3 27B IT, Gemma 4 26B A4B IT. The best choice depends on your use case: coding assistants benefit from code-tuned models, while general chat works well with instruction-tuned models like Llama or Qwen.

What power supply and cooling does NVIDIA RTX PRO 4000 Blackwell need?

The NVIDIA RTX PRO 4000 Blackwell has a TDP of 145 W. A good rule of thumb is to provide at least double the GPU's TDP to cover the rest of the system — that means a 550 W PSU or larger. It's a relatively low-power card, so most mid-tower cases with basic airflow handle it comfortably. Still, ensure the GPU slot has clearance and vents aren't obstructed during long inference sessions.