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EleutherAIGPTNeoXForCausalLM

Pythia 410M Deduped — Hardware Requirements & GPU Compatibility

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Pythia 410M Deduped is a 506M-parameter open language model from EleutherAI. It supports a context window of up to 2,048 tokens. At Q4_K_M it needs about 0.33 GB of VRAM — see which GPUs and Macs can run it below.

506M params · dense2K contextApache 2.036.4K downloads23 likes6.4K quant downloads
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Runs great on a 24 GB GPU

Runs from8 GB Q4_K_M · 2KBest on24 GB Q4_K_M · ~1986 tok/s · 2KMacs from8 GB Q4_K_M · ~217 tok/s

Apache 2.0

Reference GPU · RTX 4090 24 GB

Estimates, ±20% · how we estimate

Run Pythia 410M Deduped

One recommended way. Every other method, OS and quant is in the step-by-step guide.

Recommended

Ollama
one command · needs Ollama installed
$ollama run hf.co/mradermacher/pythia-410m-deduped-i1-GGUF:Q4_K_M

Q4_K_M fits fully on the RTX 4090 · 23.7 GB free · 2K context

Download: pythia-410m-deduped.i1-Q4_K_M.gguf0.27 GBmradermacher

install, OS, other quants

Other ways

each opens step-by-step

Run in cloud

Fits on RTX 3060 12GB (11 GB headroom) · Q4_K_M

Generation speed
~709 tok/s
generation speed
Cost per 1M output tokens
$0.032
per 1M output tokens

How Much VRAM Does Pythia 410M Deduped Need?

Select a quantization level; the listed hardware adheres to it.

QuantizationVRAM+32KOn RTX 4090 (reference)
0.2 GB—2-bit · K-quant — 2-bit quantization with K-quant improvementsFits: 2K context · ~2730 tok/s
0.2 GB—3-bit small — 3-bit small quantizationFits: 2K context · ~2730 tok/s
0.3 GB—3-bit medium — 3-bit medium quantizationFits: 2K context · ~2427 tok/s
0.3 GB—4-bit · legacy — 4-bit legacy quantizationFits: 2K context · ~2340 tok/s
0.3 GB—4-bit medium — 4-bit medium quantization — most popular sweet spotFits: 2K context · ~1986 tok/s
0.4 GB—5-bit medium — 5-bit medium quantization — good quality/size tradeoffFits: 2K context · ~1638 tok/s
0.5 GB—6-bit, very good — 6-bit quantization, very good qualityFits: 2K context · ~1424 tok/s
0.6 GB—8-bit, near-lossless — 8-bit quantization, near-losslessFits: 2K context · ~1170 tok/s

Selected Q4_K_M

4-bit medium quantization

0.3GBat 2K context

Weights
0.1 GB
KV cache
0.0 GB
Overhead
0.3 GB

Fits RTX 4090 (reference) · 23.7 GB free · ~1986 tok/s

≥50 tok/s needs ≥25 GB/s · RTX 5090 ~3530, RTX 3090 Ti ~1986

Which Hardware Can Run Pythia 410M Deduped?

Q4_K_M · 0.3 GB

Pythia 410M Deduped (Q4_K_M) requires 0.3 GB of VRAM to load the model weights. For comfortable inference with headroom for KV cache and system overhead, 1+ GB is recommended. 52 GPUs can run it, including NVIDIA GeForce RTX 5090, NVIDIA GeForce RTX 3090 Ti. 163 devices with unified memory can run Pythia 410M Deduped, including Mac Studio (M3 Ultra, 256GB), Mac Studio (M3 Ultra, 512GB).

By VRAM tier · typical GPUs and Macs at Q4_K_M
8 GB · RTX 4060Q4_K_M · 0.3 GB · ~536 tok/s · 2K8 GB tier →
12 GB · RTX 3060 12GBQ4_K_M · 0.3 GB · ~709 tok/s · 2K12 GB tier →
16 GB · RTX 5060 Ti 16GBQ4_K_M · 0.3 GB · ~882 tok/s · 2K16 GB tier →
24 GB · RTX 4090referenceQ4_K_M · 0.3 GB · ~1986 tok/s · 2K24 GB tier →
Mac 32 GB · Mac Mini M4Q4_K_M · 0.3 GB · ~255 tok/s · 2KMacs →
Mac 64 GB · Mac Studio M4 MaxQ4_K_M · 0.3 GB · ~1158 tok/s · 2KMacs →

Alternatives to Pythia 410M Deduped

Similar models

4
ModelScoreVRAMtok/sWhy it is similar
Falcon H1 0.5B BaseTII UAE—1.2 GB~950same size
Qwen2.5 0.5B InstructAlibaba—0.8 GB~1057same size
Qwen2 0.5B InstructAlibaba—0.8 GB~1057same size
Qwen3 4B DFlash B16z-lab—0.8 GB~1008same size

Specifications

Publisher
EleutherAI
Parameters
506M
Architecture
GPTNeoXForCausalLM
Context Length
2,048 tokens
Vocabulary Size
50,304
Release Date
2023-02-13
License
Apache 2.0

Frequently Asked Questions

How much VRAM does Pythia 410M Deduped need?

Pythia 410M Deduped requires 0.3 GB of VRAM at Q4_K_M, or 1.1 GB at FP16.

VRAM = Weights + KV Cache + Overhead

Weights = 506M × 4.8 bits ÷ 8 = 0.3 GB

Fit ratings and hardware model lists check this model with room for a 16K-token context, which needs a little more memory.

VRAM usage by quantization

0.3 GB

Learn more about VRAM estimation →

What's the best quantization for Pythia 410M Deduped?

For Pythia 410M Deduped, Q4_K_M (0.3 GB) offers the best balance of quality and VRAM usage. Q5_K_S (0.4 GB) provides better quality if you have the VRAM. The smallest option is IQ2_XXS at 0.1 GB.

VRAM requirement by quantization

IQ2_XXS
0.1 GB
IQ3_XS
0.2 GB
Q3_K_M
0.3 GB
Q4_K_M ★
0.3 GB
Q5_K_S
0.4 GB
FP16
1.1 GB

★ Recommended — best balance of quality and VRAM usage.

Learn more about quantization →

Can I run Pythia 410M Deduped on a Mac?

Yes — MacBook Air 13" M3 (8 GB) and 145 other Macs can run Pythia 410M Deduped. Apple Silicon uses unified memory, so the model shares RAM with the system. At Q4_K_M you need at least 0.3 GB of usable unified memory (RAM minus macOS overhead).

Can I run Pythia 410M Deduped locally?

Yes — Pythia 410M Deduped can run locally on consumer hardware. Popular tools include Ollama, LM Studio, and llama.cpp.

How fast is Pythia 410M Deduped?

At Q4_K_M, Pythia 410M Deduped can reach ~14546 tok/s on AMD Instinct MI350X. On NVIDIA GeForce RTX 4090: ~1986 tok/s. Speed depends mainly on GPU memory bandwidth. Real-world results typically within ±20%.

tok/s = (bandwidth GB/s ÷ model GB) × efficiency

Example: NVIDIA B200 → 8000 ÷ 0.33 × 0.65 = ~15758 tok/s

Estimated speed at Q4_K_M (0.3 GB)

~15758 tok/s
~1986 tok/s
~15758 tok/s
~14546 tok/s

Real-world results typically within ±20%. Speed depends on batch size, quantization kernel, and software stack.

Learn more about tok/s estimation →

What's the download size of Pythia 410M Deduped?

At Q4_K_M, the download is about 0.30 GB. The full-precision FP16 version is 1.01 GB. The smallest option (IQ2_XXS) is 0.14 GB.

Which GPUs can run Pythia 410M Deduped?

52 consumer GPUs can run Pythia 410M Deduped at Q4_K_M. Top options include AMD Radeon RX 6700 XT, AMD Radeon RX 6800, AMD Radeon RX 6800 XT. 52 GPUs have plenty of headroom for comfortable inference.

Which devices can run Pythia 410M Deduped?

163 devices with unified memory can run Pythia 410M Deduped at Q4_K_M (0.3 GB), including AMD Ryzen AI 9 HX 370 (Strix Point) Laptop, ASUS Ascent GX10, Beelink GTR9 Pro (Ryzen AI Max+ 395, 128 GB), Framework Desktop (Ryzen AI Max+ 395, 128 GB). Apple Silicon Macs use unified memory shared between CPU and GPU, making them well-suited for local LLM inference.