Mixtral 8x7B Instruct v0.1 — Hardware Requirements & GPU Compatibility
ChatMixtral 8x7B Instruct v0.1 is Mistral AI's flagship Mixture-of-Experts model, combining eight expert networks of 7 billion parameters each for a 46.7B total weight count while activating only about 12.9 billion parameters per token. This sparse architecture delivers performance that rivals much larger dense models at a fraction of the inference cost, excelling across reasoning, code generation, and multilingual tasks. Because the full weights must still be loaded into memory, you will need around 24–48 GB of VRAM depending on quantization level, making it best suited for multi-GPU desktop setups or high-VRAM workstation cards. If your hardware can accommodate it, Mixtral offers one of the best performance-per-active-parameter ratios available for local deployment.
Usable on a 24 GB GPU
Runs from 16 GB (IQ2_XXS · 16K)Best on 24 GB (IQ3_M · ~92 tok/s · 16K)Macs from 24 GB (IQ2_M · ~37 tok/s)
Score 65.8#100 of 106 open#31 of 36 that fit 24 GBApache 2.0
Reference GPU · RTX 4090 24 GB
Estimates, ±20% · how we estimate
llmrun Composite Score →
65.8
- 90% range 58.5–73.0
- #100 of 106 open models
- #31 of 36 that fit 24 GB
Run Mixtral 8x7B Instruct v0.1
One recommended way. Every other method, OS and quant is in the step-by-step guide.Each way opens a step-by-step guide for your OS and quant.
Recommended
ollama run mixtral:8x7b-instruct-v0.1-q4_K_MQ4_K_M · needs ~30.5 GB · 16K context
Download: mixtral-8x7b-instruct-v0.1.Q4_K_M.gguf26.44 GBTheBloke
Ways to runOther ways
each opens step-by-stepRun in cloud
Runs on A100 40GB (9 GB headroom) · Q4_K_M
- Generation speed
- ~105 tok/s
- generation speed
- Cost per 1M output tokens
- $1.07
- per 1M output tokens
How Much VRAM Does Mixtral 8x7B Instruct v0.1 Need?
Select a quantization level; the listed hardware adheres to it.
| Quantization | VRAM | +32K | On RTX 4090 (reference) | |
|---|---|---|---|---|
| 20.4 GB | 24.5 GB | 2-bit · K-quant — 2-bit quantization with K-quant improvements | Fits: 16K context · ~97 tok/s | |
| 21 GB | 25 GB | 3-bit small — 3-bit small quantization | Fits: 16K context · ~94 tok/s | |
| 23.3 GB | 27.4 GB | 3-bit medium — 3-bit medium quantization | Fits: 4K context · ~86 tok/s | |
| 23.9 GB | 28 GB | 4-bit · legacy — 4-bit legacy quantization | Fits: 2K context · ~85 tok/s | |
| 28.6 GB | 32.6 GB | 4-bit medium — 4-bit medium quantization — most popular sweet spot | Does not fit: needs 30.5 GB | |
| 33.8 GB | 37.9 GB | 5-bit medium — 5-bit medium quantization — good quality/size tradeoff | Does not fit: needs 35.7 GB | |
| 39.1 GB | 43.1 GB | 6-bit, very good — 6-bit quantization, very good quality | Does not fit: needs 41 GB | |
| 47.3 GB | 51.3 GB | 8-bit, near-lossless — 8-bit quantization, near-lossless | Does not fit: needs 49.2 GB |
Selected Q4_K_M
4-bit medium quantization30.5GBat 16K context
- Weights
- 28.0 GB
- KV cache
- 2.2 GB
- Overhead
- 0.3 GB
Doesn't fit RTX 4090 (reference) · needs 6.5 GB more, IQ3_M fits
≥50 tok/s needs ≥664 GB/s · RTX 5090 ~117
Or .
Which Hardware Can Run Mixtral 8x7B Instruct v0.1?
Q4_K_M · 28.6 GBMixtral 8x7B Instruct v0.1 (Q4_K_M) requires 28.6 GB of VRAM to load the model weights. For comfortable inference with headroom for KV cache and system overhead, 38+ GB is recommended. Using the full 33K context window can add up to 4.0 GB, bringing total usage to 32.6 GB. 1 GPU can run it, including NVIDIA GeForce RTX 5090. 78 devices with unified memory can run Mixtral 8x7B Instruct v0.1, including Mac Studio (M3 Ultra, 256GB), Mac Studio (M3 Ultra, 512GB), Mac Studio M5 Max (36 GB).
20 GB
Q4_K_M · best fit IQ2_M (18.2 GB)
1 GPU
RX 7900 XT~63Simulate output on RX 7900 XT32–40 GB
fits · 1.5 GB free · up to 16K ctx
1 GPU · 2 Mac classes · 1 device family
RTX 5090~117Simulate output on RTX 5090M5 Max36 GB~32Simulate output on Mac Studio M5 Max (36 GB)M3 Pro*36 GB~12Simulate output on MacBook Pro 14" M3 Pro (36 GB)Orin~16Simulate output on NVIDIA Jetson AGX Orin 32GB
By VRAM tier · typical GPUs and Macs at Q4_K_M
How good is Mixtral 8x7B Instruct v0.1?
The llmrun Score merges 4 public benchmark boards into a single figure, where 100 represents the average for open models.
Score vs VRAM in the 24 GB tier
- Mixtral 8x7B Instruct v0.1
- Other models
- Best Score for its VRAM
#31 of 36 that fit 24 GB
Each dot is a model at the best quant that fits a 24 GB GPU. The line steps up to the best Score available at each amount of VRAM; a dot below it is beaten by a model that needs no more memory.
Full 24 GB ranking →Benchmarks
Here are all 6 boards that have results for this model, sorted by their weight in the llmrun Score; badges show who ran the test.
- GPQA Diamond
Epoch AI · Dec 2023Independent
Independent30.6%
#83/100 open
- LMArena Text
LMArena · Oct 2026Arena
Arena1197.2
#148/188 open
- MMLU-Pro
TIGER-LabIndependent
Independent43.3%
#93/146 open
- MATH Level 5
Epoch AI · Dec 2023Independent
Independent10.0%
#34/39 open
- DTBench
Epoch AI · Dec 2023Lab-reported
Lab-reported49.6%
#62/70 open
- ForecastBench
Epoch AI · Dec 2023Lab-reported
Lab-reported58.2
#23/24 open
In the 24 GB class
36 models fit 24 GBSame Score, only models that fit 24 GB at their best quant: the ranking a 24 GB owner actually chooses from.
- #1
Qwen3.8 27BAlibaba
122.0
~38 tok/s · 17.9 GB
- #2
Qwen3.6 27BAlibaba
111.2
~38 tok/s · 17.9 GB
- #3
Qwen3.6 35B A3BAlibaba
106.8
~151 tok/s · 22.0 GB
- #4
Gemma 4 31B ITGoogle
106.7
~32 tok/s · 21.7 GB
- #5
Gemma 4 26B A4B ITGoogle
105.8
~171 tok/s · 16.5 GB
- #6
Qwen3.5 35B A3BAlibaba
105.8
~151 tok/s · 22.0 GB
Alternatives to Mixtral 8x7B Instruct v0.1
Mixtral family · 7 models →Official models with an llmrun Score, each answering one question; numbers are at the best quant that fits a 24 GB GPU.
Best alternative at this size
Qwen3.8 27B
Alibaba
- 56.2 higher Score
- 5.6 GB less VRAM
- 55 tok/s slower
Score 122.0 · 17.9 GB · ~38 tok/s
Much faster, similar quality
Qwen3.6 35B A3B
Alibaba
- 41 higher Score
- 1.4 GB less VRAM
- 59 tok/s faster
Score 106.8 · 22 GB · ~151 tok/s
Fits in less VRAM
GPT OSS 20B
OpenAI
- 30.6 higher Score
- 10.3 GB less VRAM
- 97 tok/s faster
Score 96.4 · 13.1 GB · ~190 tok/s
Other vendor
Qwen3.6 27B
Alibaba
- 45.4 higher Score
- 5.6 GB less VRAM
- 55 tok/s slower
Score 111.2 · 17.9 GB · ~38 tok/s
Similar models
10| Model | Score | VRAM | tok/s | Why it is similar |
|---|---|---|---|---|
| Gemma 4 31B ITGoogle | 106.7 | 21.7 GB | ~32 | similar score |
| Gemma 4 26B A4B ITGoogle | 105.8 | 16.5 GB | ~171 | similar score |
| Qwen3.5 35B A3BAlibaba | 105.8 | 22 GB | ~151 | similar score |
| Qwen3.5 27BAlibaba | 103.8 | 17.9 GB | ~38 | similar score |
| Seed OSS 36B InstructByteDance-Seed | 102.5 | 22.8 GB | ~31 | similar score |
| Qwen3 30B A3B Thinking 2507Alibaba | 100.7 | 19.4 GB | ~173 | similar score |
| Mistral Nemo Instruct 2407Mistral AI | 65.4 | 11 GB | ~81 | similar score |
| Qwen2.5 7B InstructAlibaba | 65.1 | 5.8 GB | ~131 | similar score |
| Gemma 3 4B ITGoogle | 64.0 | 5 GB | ~231 | similar score |
| DeepSeek R1 Distill Qwen 32BDeepSeek | 97.2 | 23 GB | ~34 | same size |
Specifications
- Publisher
- Mistral AI
- Family
- Mixtral
- Parameters
- 46.7B
- Active parameters
- 12.9B per token
- Architecture
- MixtralForCausalLM
- Context Length
- 32,768 tokens
- Vocabulary Size
- 32,000
- Release Date
- 2023-12-10
- License
- Apache 2.0
Frequently Asked Questions
How much VRAM does Mixtral 8x7B Instruct v0.1 need?
Mixtral 8x7B Instruct v0.1 requires 28.6 GB of VRAM at Q4_K_M, or 94.0 GB at BF16. Full 33K context adds up to 4.0 GB (32.6 GB total).
VRAM = Weights + KV Cache + Overhead
Weights = 46.7B × 4.8 bits ÷ 8 = 28 GB
KV Cache + Overhead ≈ 0.6 GB (at 2K context + ~0.3 GB framework)
Fit ratings and hardware model lists check this model with room for a 16K-token context, which needs a little more memory.
KV Cache + Overhead ≈ 4.6 GB (at full 33K context)
VRAM usage by quantization
Can NVIDIA GeForce RTX 4090 run Mixtral 8x7B Instruct v0.1?
Yes, at Q4_0 (23.9 GB) or lower. Higher quantizations like Q3_K_L (24.5 GB) exceed the NVIDIA GeForce RTX 4090's 24 GB.
What's the best quantization for Mixtral 8x7B Instruct v0.1?
For Mixtral 8x7B Instruct v0.1, Q4_K_M (28.6 GB) offers the best balance of quality and VRAM usage. Q5_0 (29.8 GB) provides better quality if you have the VRAM. The smallest option is IQ2_XXS at 13.4 GB.
VRAM requirement by quantization
★ Recommended — best balance of quality and VRAM usage.
Can I run Mixtral 8x7B Instruct v0.1 on a Mac?
Yes — Mac Mini M5 Pro (24 GB) and 106 other Macs can run Mixtral 8x7B Instruct v0.1, the smallest at IQ2_M. Apple Silicon uses unified memory, so the model shares RAM with the system. At Q4_K_M you need at least 28.6 GB of usable unified memory (RAM minus macOS overhead), from Mac Studio M5 Max (36 GB).
Can I run Mixtral 8x7B Instruct v0.1 locally?
Yes — Mixtral 8x7B Instruct v0.1 can run locally on consumer hardware. Popular tools include Ollama, LM Studio, and llama.cpp.
How fast is Mixtral 8x7B Instruct v0.1?
At Q4_K_M, Mixtral 8x7B Instruct v0.1 can reach ~124 tok/s on AMD Instinct MI350X. Speed depends mainly on GPU memory bandwidth. Real-world results typically within ±20%.
tok/s = 1000 ÷ (active GB ÷ (bandwidth GB/s × efficiency) × 1000 + layers × routing ms)
Mixture-of-Experts: just the active experts get read for each token, along with a fixed routing cost per layer.
Example: NVIDIA B200 → 7.9 GB active ÷ (8000 × 0.65) = 1.52 ms, plus 32 layers × 0.055 ms = 1.76 ms, so 1000 ÷ 3.28 ms = ~305 tok/s
Estimated speed at Q4_K_M (28.6 GB)
Real-world results typically within ±20%. Speed depends on batch size, quantization kernel, and software stack.
What's the download size of Mixtral 8x7B Instruct v0.1?
At Q4_K_M, the download is about 28.02 GB. The full-precision BF16 version is 93.41 GB. The smallest option (IQ2_XXS) is 12.84 GB.
Which GPUs can run Mixtral 8x7B Instruct v0.1?
1 consumer GPU can run Mixtral 8x7B Instruct v0.1 at Q4_K_M. Top options include NVIDIA GeForce RTX 5090.
Which devices can run Mixtral 8x7B Instruct v0.1?
78 devices with unified memory can run Mixtral 8x7B Instruct v0.1 at Q4_K_M (28.6 GB), including ASUS Ascent GX10, Beelink GTR9 Pro (Ryzen AI Max+ 395, 128 GB), Framework Desktop (Ryzen AI Max+ 395, 128 GB), GMKtec EVO-X2 (Ryzen AI Max+ 395, 128 GB). Apple Silicon Macs use unified memory shared between CPU and GPU, making them well-suited for local LLM inference.