llmrun

AMD · 8x Instinct MI355X (OAM, UBB 2.0) · Server

Best AI Models for AMD Instinct MI355X Platform (8x MI355X) (2.3 TB)

Runs models up to 2.8T parameters, like Kimi K3.1 Pro.

2.3 TB HBM64 TB/s20.1 PFLOPS FP162025

What LLMs can the AMD Instinct MI355X Platform (8x MI355X) run?

#ModelSpeedllmrun ScoreQuant · Memory
1
Q4_K_M · 1712.1 GB · 49.4 t/s
49.4 tok/sQ4_K_M · 1712.1 GB
2
Inkling 2 SmallThinking Machines
Q4_K_M · 359.1 GB · 93.8 t/s
93.8 tok/sQ4_K_M · 359.1 GB
3
Q4_K_M · 458.4 GB · 111 t/s
111 tok/sQ4_K_M · 458.4 GB
4
Q4_K_M · 614.1 GB · 65.3 t/s
65.3 tok/sQ4_K_M · 614.1 GB
5
Q4_K_M · 19.6 GB · 262 t/s
262 tok/sQ4_K_M · 19.6 GB

About the AMD Instinct MI355X Platform (8x MI355X)

The AMD Instinct MI355X Platform (8x MI355X) runs models up to 2.8T parameters, like Kimi K3.1 Pro. A 4K-token prompt waits 200 ms before the first word on Kimi K3.1 Pro. 8x Instinct MI355X (OAM, UBB 2.0) (CDNA 4), released 2025.

For models2.3 TBall of it
Chip8x Instinct MI355X (OAM, UBB 2.0)released 2025

AMD Instinct MI355X Platform (8x MI355X) strengths and weaknesses

Strengths

  • Runs 120B MoE models: GPT OSS 120B at 126 tok/s in 70.8 GB
  • Room for long context: Llama 3.3 70B Instruct at Q4 uses 51.3 GB, leaving 2.3 TB free
  • Reads long prompts fast: A 32K-token prompt on Kimi K3.1 Pro starts answering in 1.6 s

Memory for models

2.3 TB of 2.3 TB
120B MoE70.8 GB2780B1712.1 GB
120B MoE70.8 GB2780B1712.1 GB
For models 2.3 TBModel size at Q4

Everything on the size ladder fits. Kimi K3.1 Pro and MiMo V2.6 Flash RL together use 1.9 TB and leave 405.4 GB free.

Similar devices and alternatives

The same chip from other makers first, then machines and GPUs people weigh against it, each with the one reason it is worth a look. Speeds on Qwen3.6 35B A3B.

AMD Instinct MI355X Platform (8x MI355X) tokens per second by model size

Output speed depends on memory bandwidth: each model runs on as few of the 8 GPUs as hold it, at 8 TB/s per GPU. Grey rows need more than the 2.3 TB available.

  1. 9BQwen3.5 9B · Q4_K_M · 6.6 GB
    755tok/s
  2. 14BQwen3 14B · Q4_K_M · 11.9 GB
    505tok/s
  3. 27–31BQwen3.8 27B · Q4_K_M · 17.9 GB
    276tok/s
  4. 35B MoEQwen3.6 35B A3B · Q4_K_M · 22.0 GB
    116tok/s
  5. 70BLlama 3.3 70B Instruct · Q4_K_M · 51.3 GB
    103tok/s
  6. 120B MoEGPT OSS 120B · Q4_K_M · 70.8 GB
    126tok/s

Estimated speeds: Q4_K_M, 4K context, one user. How we estimate

All 454 models on the AMD Instinct MI355X Platform (8x MI355X)

Featured only

Best quant that fits in 2304 GB, ordered by llmrun Score. Fit grades how well it runs here, S best. How ranking works

LLM models compatible with AMD Instinct MI355X Platform (8x MI355X) — ranked by Score, recency and Fit
ModelVRAMScoreFit
Q4_K_M·229.6 t/s
24.7 GBS100, Runs great
Llama 3.1 405B Instruct
Q4_K_M·17.9 t/s
275.6 GBB58, Decent
Mixtral 8x22B Instruct v0.1
Q4_K_M·62.0 t/s
88.4 GBA84, Runs well
C4ai Command R 08 2024
Q4_K_M·225.1 t/s
25.1 GBS100, Runs great
DeepSeek v3 0324
Q4_K_M·67.9 t/s
412.2 GBS85, Runs great
Llama 3.1 8B Instruct
Q4_K_M·905.7 t/s
7.9 GBS100, Runs great
Q4_K_M·1315.1 t/s
6.0 GBS100, Runs great
BF16·85.8 t/s
573.0 GBS88, Runs great
DeepSeek v3
Q4_K_M·67.9 t/s
412.1 GBS85, Runs great
Q4_K_M·4752.5 t/s
1.0 GBS100, Runs great
Qwen2.5 Coder 32B Instruct
Q4_K_M·234.1 t/s
24.3 GBS100, Runs great
Gemma 3 27B IT
Q4_K_M·265.0 t/s
21.7 GBS100, Runs great
Q4_K_M·786.9 t/s
7.3 GBS100, Runs great
Qwen3 VL 2B Instruct
Q4_K_M·2651.9 t/s
3.5 GBS100, Runs great
FP16·288.3 t/s
19.2 GBS100, Runs great

AMD Instinct MI355X Platform (8x MI355X) specs

Specs

Chip
8x Instinct MI355X (OAM, UBB 2.0) · AMD Instinct MI355X
GPU cores
131,072
Memory
2.3 TB
For models
2.3 TB
Memory bandwidth
64 TB/s
FP16 (dense)
20.1 PFLOPS
Released
2025-06-12

AMD Instinct MI355X Platform (8x MI355X) FAQ

How much memory is available for AI on the AMD Instinct MI355X Platform (8x MI355X)?

All 2.3 TB can hold model weights.

What is the largest model the AMD Instinct MI355X Platform (8x MI355X) can run?

Kimi K3.1 Pro (2780.1B) is the largest at 4-bit or better: at Q4_K_M it uses 1712.1 GB, 74% of the available memory, and runs at about 49.4 tok/s.

How long does the AMD Instinct MI355X Platform (8x MI355X) take to read a long prompt?

On Kimi K3.1 Pro, about 200 ms for a 4K-token prompt and 1.6 s for a 32K-token document before the first word appears.