llmrun

NVIDIA · 72x Blackwell Ultra + 36x Grace · Server

Best AI Models for NVIDIA GB300 NVL72 (20.7 TB)

Runs models up to 2.8T parameters, like Kimi K3.1 Pro.

20.7 TB HBM576 TB/s180 PFLOPS FP16135 kW2025

What LLMs can the NVIDIA GB300 NVL72 run?

#ModelSpeedllmrun ScoreQuant · Memory
1
Q4_K_M · 1712.1 GB · 150 t/s
150 tok/sQ4_K_M · 1712.1 GB
2
Inkling 2 SmallThinking Machines
Q4_K_M · 359.1 GB · 276 t/s
276 tok/sQ4_K_M · 359.1 GB
3
Q4_K_M · 458.4 GB · 320 t/s
320 tok/sQ4_K_M · 458.4 GB
4
Q4_K_M · 614.1 GB · 198 t/s
198 tok/sQ4_K_M · 614.1 GB
5
Hy3Tencent
Q4_K_M · 182.3 GB · 147 t/s
147 tok/sQ4_K_M · 182.3 GB
See all 455 models on the NVIDIA GB300 NVL72 →Bars = traction for models without a Score yet

About the NVIDIA GB300 NVL72

The NVIDIA GB300 NVL72 runs models up to 2.8T parameters, like Kimi K3.1 Pro. A 4K-token prompt waits 100 ms before the first word on Kimi K3.1 Pro. 72x Blackwell Ultra + 36x Grace (Blackwell Ultra), released 2025.

For models20.7 TBall of it
Chip72x Blackwell Ultra + 36x Gracereleased 2025

NVIDIA GB300 NVL72 strengths and weaknesses

Strengths

  • Runs 120B MoE models: GPT OSS 120B at 378 tok/s in 70.8 GB
  • Room for long context: Llama 3.3 70B Instruct at Q4 uses 51.3 GB, leaving 20.7 TB free
  • Reads long prompts fast: A 32K-token prompt on Kimi K3.1 Pro starts answering in 770 ms
  • FP8 and NVFP4 run natively: Blackwell takes FP8 and NVFP4 checkpoints in vLLM as published

Memory for models

20.7 TB of 20.7 TB
For models 20.7 TBModel size at Q4

Everything on the size ladder fits. Kimi K3.1 Pro and Inkling 2 Small together use 2.1 TB and leave 18.7 TB free.

Similar devices and alternatives

The same chip from other makers first, then machines and GPUs people weigh against it, each with the one reason it is worth a look. Speeds on Qwen3.6 35B A3B.

NVIDIA GB300 NVL72 tokens per second by model size

Output speed depends on memory bandwidth: each model runs on as few of the 72 GPUs as hold it, at 8 TB/s per GPU. Grey rows need more than the 20.7 TB available.

  1. 9BQwen3.5 9B · Q4_K_M · 6.6 GB
    818tok/s
  2. 14BQwen3 14B · Q4_K_M · 11.9 GB
    547tok/s
  3. 27–31BQwen3.8 27B · Q4_K_M · 17.9 GB
    299tok/s
  4. 35B MoEQwen3.6 35B A3B · Q4_K_M · 22.0 GB
    363tok/s
  5. 70BLlama 3.3 70B Instruct · Q4_K_M · 51.3 GB
    112tok/s
  6. 120B MoEGPT OSS 120B · Q4_K_M · 70.8 GB
    378tok/s

Estimated speeds: Q4_K_M, 4K context, one user. How we estimate

All 1392 models on the NVIDIA GB300 NVL72

Featured only

Best quant that fits in 20736 GB, ordered by llmrun Score. Fit grades how well it runs here, S best. How ranking works

LLM models compatible with NVIDIA GB300 NVL72 — ranked by Score, recency and Fit
ModelVRAMScoreFit
Qwen3.5 397B A17B
Q4_K_M·163.4 t/s
242.6 GBS97, Runs great
Qwen3.5 9B
Q4_K_M·817.6 t/s
6.6 GBS100, Runs great
GLM 5
Q4_K_M·148.0 t/s
454.1 GBS97, Runs great
Q4_K_M·331.0 t/s
27.0 GBS100, Runs great
Qwen3.5 122B A10B
Q4_K_M·242.8 t/s
75.5 GBS100, Runs great
GLM 4.7 Flash
Q4_K_M·317.7 t/s
19.9 GBS100, Runs great
Qwen3.5 4B
Q4_K_M·1595.1 t/s
3.4 GBS100, Runs great
Arete 27B
Q4_K_M·303.0 t/s
17.6 GBS100, Runs great
Spark X2.6 4B
Q4_K_M·1756.8 t/s
4.3 GBS100, Runs great
Gemma 4 12B IT
Q4_K_M·631.8 t/s
9.0 GBS100, Runs great
MiniCPM5 2B
Q4_K_M·2736.8 t/s
2.5 GBS100, Runs great
DeepSeek V3.2
Q4_K_M·174.2 t/s
412.7 GBS98, Runs great
Q4_K_M·298.5 t/s
17.9 GBS100, Runs great
Hy Memory 30B A3B
Q4_K_M·334.0 t/s
19.1 GBS100, Runs great
Q4_K_M·977.4 t/s
5.6 GBS100, Runs great

NVIDIA GB300 NVL72 specs and power

Specs

Chip
72x Blackwell Ultra + 36x Grace · NVIDIA B300 (Blackwell Ultra, GB300)
CPU cores
2592
GPU cores
1,474,560
Memory
20.7 TB
For models
20.7 TB
Memory bandwidth
576 TB/s
FP16 (dense)
180 PFLOPS
Power
135 kW max
Released
2025-07-03

NVIDIA GB300 NVL72 FAQ

How much memory is available for AI on the NVIDIA GB300 NVL72?

All 20.7 TB can hold model weights.

What is the largest model the NVIDIA GB300 NVL72 can run?

Kimi K3.1 Pro (2780.1B) is the largest at 4-bit or better: at Q4_K_M it uses 1712.1 GB, 8% of the available memory, and runs at about 150 tok/s.

How long does the NVIDIA GB300 NVL72 take to read a long prompt?

On Kimi K3.1 Pro, about 100 ms for a 4K-token prompt and 770 ms for a 32K-token document before the first word appears.