NVIDIAAda Lovelace

Best AI Models for NVIDIA L40S (48.0GB)

VRAM:48.0 GB GDDR6·Bandwidth:864.0 GB/s·CUDA Cores:18,176·TDP:350W

With 48 GB of memory, this is a high-end configuration for local AI. You can comfortably run most open-source LLMs including large 70B parameter models at good quantization levels, making it one of the best setups for serious local AI work.

At this memory tier, nearly every popular open-source model is within reach. You can run Llama 3 70B at Q4_K_M or even Q5_K_M quantization with room to spare, handle coding assistants like DeepSeek Coder 33B at high quality, and easily run any 7B–30B model at full or near-full precision. Context windows remain generous even with larger models, so multi-turn conversations and long-document processing work smoothly.

Runs Well

  • 70B models (Llama 3 70B, Qwen 72B) at Q4–Q5
  • 30B models at Q6–Q8 quality
  • 7B–14B models at full FP16 precision
  • Vision models (LLaVA, CogVLM) without compromise

Challenging

  • Mixture-of-experts models like Mixtral 8x22B at higher quants
  • 120B+ models still require lower quantizations

What LLMs Can NVIDIA L40S Run?

113 models · 5 good

Showing compatibility for NVIDIA L40S

LLM models compatible with NVIDIA L40S — ranked by performance
ModelVRAMGrade
Q4_K_M·19.6 t/s tok/s·33K ctx·GOOD FIT
28.6 GBA76
Q4_K_M·19.6 t/s tok/s·33K ctx·GOOD FIT
28.6 GBA76
Falcon 40B41.8B
Q4_K_M·20.3 t/s tok/s·GOOD FIT
27.6 GBA74
Phi 3.5 MoE Instruct41.9B
Q4_K_M·21.9 t/s tok/s·131K ctx·GOOD FIT
25.7 GBA69
Qwen3.6 35B A3B36.0B
Q4_K_M·25.6 t/s tok/s·262K ctx·FAIR FIT
21.9 GBB61
Gemma 4 31B IT32.7B
Q4_K_M·26.5 t/s tok/s·262K ctx·FAIR FIT
21.2 GBB59
Q4_K_M·21.3 t/s tok/s·GOOD FIT
26.4 GBA70
Q4_K_M·27.4 t/s tok/s·33K ctx·FAIR FIT
20.5 GBB58
Qwen3 32B32.8B
Q4_K_M·27.7 t/s tok/s·41K ctx·FAIR FIT
20.3 GBB57
Q4_K_M·33.9 t/s tok/s·262K ctx·FAIR FIT
16.6 GBB50
Q4_K_M·27.4 t/s tok/s·131K ctx·FAIR FIT
20.5 GBB58
Q4_K_M·30.0 t/s tok/s·262K ctx·FAIR FIT
18.7 GBB54
Q4_K_M·24.3 t/s tok/s·FAIR FIT
23.1 GBB63
Qwen3.6 27B27.8B
Q4_K_M·32.2 t/s tok/s·262K ctx·FAIR FIT
17.4 GBB51
Gemma 3 27B IT27.4B
Q4_K_M·31.0 t/s tok/s·131K ctx·FAIR FIT
18.1 GBB53
Q4_K_M·30.0 t/s tok/s·262K ctx·FAIR FIT
18.7 GBB54

NVIDIA L40S Specifications

Brand
NVIDIA
Architecture
Ada Lovelace
Compute Capability
8.9 (CUDA SM version)
VRAM
48.0 GB GDDR6
Memory Bandwidth
864.0 GB/s
CUDA Cores
18,176
Tensor Cores
568
FP16 Performance
366.50 TFLOPS
TDP
350W
Release Date
2023-08-08

Get Started

Ollama (Recommended)

$curl -fsSL https://ollama.com/install.sh | sh
$ollama run llama3:8b

LM Studio

LM Studio

Download LM Studio, search for a model, and run it with one click.

GPUs to Consider Over NVIDIA L40S

Similar GPUs and upgrades with more VRAM or higher bandwidth for AI

Frequently Asked Questions

Can NVIDIA L40S run Mixtral 8x7B Instruct v0.1?

Yes, the NVIDIA L40S with 48 GB can run Mixtral 8x7B Instruct v0.1, Mixtral 8x7B v0.1, Falcon 40B, and 1334 other models. 11 models run at excellent quality, and 31 at good quality. Check the compatibility table above for the full list with VRAM usage and estimated speed.

Is NVIDIA L40S good for AI?

The NVIDIA L40S has 48 GB of GDDR6, making it excellent for running local AI models. It supports 42 models at good quality or better. With 864.0 GB/s memory bandwidth, it delivers fast token generation speeds. This is an enthusiast-grade GPU that handles most popular open-source LLMs.

How many parameters can NVIDIA L40S handle?

With 48 GB, the NVIDIA L40S supports models from 3B to 70B+ parameters depending on quantization level. At Q4_K_M (the recommended sweet spot), you can fit roughly 80B parameters. This means 7B models at high quality (Q6/Q8) or 30B+ models at Q4.

What quantization should I use on NVIDIA L40S?

For the best balance of quality and speed on the NVIDIA L40S, start with Q4_K_M — it preserves ~85% of the original model quality while keeping VRAM usage reasonable. With 24+ GB, you have the headroom to run 7B models at Q5_K_M or even Q6_K for noticeably better output quality. For larger 30B models, Q4_K_M remains the sweet spot.

How fast is NVIDIA L40S for AI inference?

With 864.0 GB/s memory bandwidth, the NVIDIA L40S achieves approximately 125 tokens/sec on a 7B model at Q4_K_M — that's very fast, well above conversational speed. A 14B model runs at ~62 tok/s. Token generation speed scales inversely with model size — smaller models are significantly faster.

tok/s = (864 GB/s ÷ model GB) × efficiency

Smaller models = faster inference. Memory bandwidth is the main bottleneck for token generation speed.

Estimated speed on NVIDIA L40S

Real-world results typically within ±20%. Speed depends on quantization kernel, batch size, and software stack.

Learn more about tok/s estimation →

What's the best model for NVIDIA L40S?

The top-rated models for the NVIDIA L40S are Mixtral 8x7B Instruct v0.1, Mixtral 8x7B v0.1, Falcon 40B. The best choice depends on your use case: coding assistants benefit from code-tuned models, while general chat works well with instruction-tuned models like Llama or Qwen.

What power supply and cooling does NVIDIA L40S need?

The NVIDIA L40S has a TDP of 350 W. A good rule of thumb is to provide at least double the GPU's TDP to cover the rest of the system — that means a 750 W PSU or larger. At this power level, a high-airflow case matters: aim for at least two front intake fans and one rear exhaust, with tidy cabling so hot air isn't trapped around the card. LLM inference sustains full GPU load continuously — longer and more consistently than most gaming workloads — so also make sure your CPU cooler can keep up under combined load.