Best AI Models for AMD Radeon PRO W7900 (48.0GB)
With 48 GB of memory, this is a high-end configuration for local AI. You can comfortably run most open-source LLMs including large 70B parameter models at good quantization levels, making it one of the best setups for serious local AI work.
At this memory tier, nearly every popular open-source model is within reach. You can run Llama 3 70B at Q4_K_M or even Q5_K_M quantization with room to spare, handle coding assistants like DeepSeek Coder 33B at high quality, and easily run any 7B–30B model at full or near-full precision. Context windows remain generous even with larger models, so multi-turn conversations and long-document processing work smoothly.
Runs Well
- 70B models (Llama 3 70B, Qwen 72B) at Q4–Q5
- 30B models at Q6–Q8 quality
- 7B–14B models at full FP16 precision
- Vision models (LLaVA, CogVLM) without compromise
Challenging
- Mixture-of-experts models like Mixtral 8x22B at higher quants
- 120B+ models still require lower quantizations
What LLMs Can AMD Radeon PRO W7900 Run?
32 models · 1 good
Showing compatibility for AMD Radeon PRO W7900
| Model | Quant | VRAM | Speed | Context | Status | Grade |
|---|---|---|---|---|---|---|
Q4_K_M·16.6 t/s tok/s·33K ctx·GOOD FIT | Q4_K_M | 28.6 GB | 16.6 t/s | 33K | GOOD FIT | A76 |
Q4_K_M·24.0 t/s tok/s·41K ctx·FAIR FIT | Q4_K_M | 19.8 GB | 24.0 t/s | 41K | FAIR FIT | B56 |
Q4_K_M·23.2 t/s tok/s·131K ctx·FAIR FIT | Q4_K_M | 20.5 GB | 23.2 t/s | 131K | FAIR FIT | B58 |
Q4_K_M·23.2 t/s tok/s·33K ctx·FAIR FIT | Q4_K_M | 20.5 GB | 23.2 t/s | 33K | FAIR FIT | B58 |
Q4_K_M·26.2 t/s tok/s·131K ctx·FAIR FIT | Q4_K_M | 18.1 GB | 26.2 t/s | 131K | FAIR FIT | B53 |
Q4_K_M·22.2 t/s tok/s·4K ctx·FAIR FIT | Q4_K_M | 21.4 GB | 22.2 t/s | 4K | FAIR FIT | B60 |
Q4_K_M·23.7 t/s tok/s·41K ctx·FAIR FIT | Q4_K_M | 20.0 GB | 23.7 t/s | 41K | FAIR FIT | B57 |
Q4_K_M·35.8 t/s tok/s·131K ctx·EASY RUN | Q4_K_M | 13.3 GB | 35.8 t/s | 131K | EASY RUN | C43 |
Q4_K_M·26.4 t/s tok/s·8K ctx·FAIR FIT | Q4_K_M | 18.0 GB | 26.4 t/s | 8K | FAIR FIT | B52 |
Q4_K_M·52.1 t/s tok/s·16K ctx·EASY RUN | Q4_K_M | 9.1 GB | 52.1 t/s | 16K | EASY RUN | C35 |
Q4_K_M·60.0 t/s tok/s·33K ctx·EASY RUN | Q4_K_M | 7.9 GB | 60.0 t/s | 33K | EASY RUN | C34 |
Q4_K_M·95.2 t/s tok/s·33K ctx·EASY RUN | Q4_K_M | 5.0 GB | 95.2 t/s | 33K | EASY RUN | C30 |
Q4_K_M·31.4 t/s tok/s·33K ctx·FAIR FIT | Q4_K_M | 15.1 GB | 31.4 t/s | 33K | FAIR FIT | B47 |
Q4_K_M·86.1 t/s tok/s·41K ctx·EASY RUN | Q4_K_M | 5.5 GB | 86.1 t/s | 41K | EASY RUN | C31 |
Q4_K_M·90.0 t/s tok/s·131K ctx·EASY RUN | Q4_K_M | 5.3 GB | 90.0 t/s | 131K | EASY RUN | C31 |
Q4_K_M·96.6 t/s tok/s·33K ctx·EASY RUN | Q4_K_M | 4.9 GB | 96.6 t/s | 33K | EASY RUN | C30 |
AMD Radeon PRO W7900 Specifications
- Brand
- AMD
- Architecture
- RDNA 3
- VRAM
- 48.0 GB GDDR6
- Memory Bandwidth
- 864.0 GB/s
- Stream Processors
- 6,144
- FP16 Performance
- 122.60 TFLOPS
- TDP
- 295W
- Release Date
- 2023-04-13
- MSRP
- $3,999
Get Started
GPUs to Consider Over AMD Radeon PRO W7900
Similar GPUs and upgrades with more VRAM or higher bandwidth for AI
NVIDIA H100 SXM
NVIDIA · Hopper
NVIDIA A100 80GB SXM
NVIDIA · Ampere
NVIDIA H100 PCIe
NVIDIA · Hopper
AMD Instinct MI210
AMD · CDNA 2
NVIDIA RTX 6000 Ada Generation
NVIDIA · Ada Lovelace
Frequently Asked Questions
- Can AMD Radeon PRO W7900 run Mixtral 8x7B Instruct v0.1?
Yes, the AMD Radeon PRO W7900 with 48 GB can run Mixtral 8x7B Instruct v0.1, Qwen3 32B, DeepSeek R1 Distill Qwen 32B, and 1221 other models. 12 models run at excellent quality, and 39 at good quality. Check the compatibility table above for the full list with VRAM usage and estimated speed.
- Is AMD Radeon PRO W7900 good for AI?
The AMD Radeon PRO W7900 has 48 GB of GDDR6, making it excellent for running local AI models. It supports 51 models at good quality or better. With 864.0 GB/s memory bandwidth, it delivers fast token generation speeds. This is an enthusiast-grade GPU that handles most popular open-source LLMs.
- How many parameters can AMD Radeon PRO W7900 handle?
With 48 GB, the AMD Radeon PRO W7900 supports models from 3B to 70B+ parameters depending on quantization level. At Q4_K_M (the recommended sweet spot), you can fit roughly 80B parameters. This means 7B models at high quality (Q6/Q8) or 30B+ models at Q4.
- What quantization should I use on AMD Radeon PRO W7900?
For the best balance of quality and speed on the AMD Radeon PRO W7900, start with Q4_K_M — it preserves ~85% of the original model quality while keeping VRAM usage reasonable. With 24+ GB, you have the headroom to run 7B models at Q5_K_M or even Q6_K for noticeably better output quality. For larger 30B models, Q4_K_M remains the sweet spot.
- How fast is AMD Radeon PRO W7900 for AI inference?
With 864.0 GB/s memory bandwidth, the AMD Radeon PRO W7900 achieves approximately 106 tokens/sec on a 7B model at Q4_K_M — that's very fast, well above conversational speed. A 14B model runs at ~53 tok/s. Token generation speed scales inversely with model size — smaller models are significantly faster.
tok/s = (864 GB/s ÷ model GB) × efficiency
Smaller models = faster inference. Memory bandwidth is the main bottleneck for token generation speed.
Estimated speed on AMD Radeon PRO W7900
~17 tok/s~24 tok/s~23 tok/s~23 tok/sReal-world results typically within ±20%. Speed depends on quantization kernel, batch size, and software stack.
- What's the best model for AMD Radeon PRO W7900?
The top-rated models for the AMD Radeon PRO W7900 are Mixtral 8x7B Instruct v0.1, Qwen3 32B, DeepSeek R1 Distill Qwen 32B. The best choice depends on your use case: coding assistants benefit from code-tuned models, while general chat works well with instruction-tuned models like Llama or Qwen.