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OpenBMBMiniCPMMiniCPMO

MiniCPM O 4 5 — Hardware Requirements & GPU Compatibility

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MiniCPM-o 4.5 is OpenBMB's roughly 9.4-billion-parameter omni-modal model, successor to MiniCPM-o 2.6, built from a SigLip2 vision encoder, a Whisper-medium audio encoder, a CosyVoice2 speech decoder, and a Qwen3-8B language backbone. It processes images, video, and audio and can generate spoken output, adding full-duplex live streaming so it can see, listen, and speak at once, plus a proactive mode that lets it comment unprompted, and bundled instruct and thinking modes. At this size it needs a high-end consumer GPU once quantized. Context length is 40,960 tokens. It is released under the Apache 2.0 license, permitting unrestricted commercial and research use, and was published in February 2026. Its defining upgrade over 2.6 is full-duplex interaction: earlier omni models process input and generate output in alternating turns, while 4.5 streams both directions at once without blocking.

9.4B params · dense41K contextApache 2.0193.5K downloads1.6K likes131.0K quant downloads
S

Runs great on a 24 GB GPU

Runs from8 GB Q4_K_M · 8KBest on24 GB Q4_K_M · ~105 tok/s · 40KMacs from16 GB Q4_K_M · ~23 tok/s

Apache 2.0

Reference GPU · RTX 4090 24 GB

Estimates, ±20% · how we estimate

Run MiniCPM O 4 5

One recommended way. Every other method, OS and quant is in the step-by-step guide.Each way opens a step-by-step guide for your OS and quant.

Recommended

Ollama
one command · needs Ollama installed
$ollama run hf.co/openbmb/MiniCPM-o-4_5-gguf:Q4_K_M

Q4_K_M fits fully on the RTX 4090 · 15.7 GB free · 16K context

Download: MiniCPM-o-4_5-Q4_K_M.gguf5.03 GBopenbmb

install, OS, other quants

Ways to runOther ways

each opens step-by-step

Run in cloud

Your own private copy · Q4_K_M · 24 GB GPU

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How Much VRAM Does MiniCPM O 4 5 Need?

Select a quantization level; the listed hardware adheres to it.

QuantizationVRAM+32KOn RTX 4090 (reference)
4.6 GB9.1 GB2-bit · K-quant — 2-bit quantization with K-quant improvementsFits: 40K context · ~143 tok/s
5.2 GB9.7 GB3-bit medium — 3-bit medium quantizationFits: 40K context · ~127 tok/s
5.3 GB9.8 GB4-bit · legacy — 4-bit legacy quantizationFits: 40K context · ~124 tok/s
5.9 GB10.4 GB4-bit small — 4-bit small quantizationFits: 40K context · ~112 tok/s
6.2 GB10.8 GB4-bit medium — 4-bit medium quantization — most popular sweet spotFits: 40K context · ~105 tok/s
7.3 GB11.8 GB5-bit medium — 5-bit medium quantization — good quality/size tradeoffFits: 40K context · ~90 tok/s
8.3 GB12.9 GB6-bit, very good — 6-bit quantization, very good qualityFits: 40K context · ~79 tok/s
10.0 GB14.5 GB8-bit, near-lossless — 8-bit quantization, near-losslessFits: 40K context · ~66 tok/s
est.calculated, no published file yet

Selected Q4_K_M

4-bit medium quantization

8.3GBat 16K context

Weights
5.6 GB
KV cache
2.4 GB
Overhead
0.3 GB

Fits RTX 4090 (reference) · 15.7 GB free · ~105 tok/s

≥50 tok/s needs ≥479 GB/s · RTX 5090 ~187, RTX 3090 Ti ~105

Which Hardware Can Run MiniCPM O 4 5?

Q4_K_M · 6.2 GB

MiniCPM O 4 5 (Q4_K_M) requires 6.2 GB of VRAM to load the model weights. For comfortable inference with headroom for KV cache and system overhead, 9+ GB is recommended. Using the full 41K context window can add up to 5.7 GB, bringing total usage to 12.0 GB. 52 GPUs can run it, including NVIDIA GeForce RTX 5090, NVIDIA GeForce RTX 3090 Ti, NVIDIA GeForce RTX 3070 Ti. 151 devices with unified memory can run MiniCPM O 4 5, including Mac Studio (M3 Ultra, 256GB), Mac Studio (M3 Ultra, 512GB), NVIDIA Jetson Orin Nano 8GB (Super).

By VRAM tier · typical GPUs and Macs at Q4_K_M
8 GB · RTX 4060Q4_K_M · 8.3 GB · ~28 tok/s · 8Ktight8 GB tier →
12 GB · RTX 3060 12GBQ4_K_M · 8.3 GB · ~38 tok/s · 40K12 GB tier →
16 GB · RTX 5060 Ti 16GBQ4_K_M · 8.3 GB · ~47 tok/s · 40K16 GB tier →
24 GB · RTX 4090referenceQ4_K_M · 8.3 GB · ~105 tok/s · 40K24 GB tier →
Mac 32 GB · Mac Mini M4Q4_K_M · 8.3 GB · ~14 tok/s · 40KMacs →
Mac 64 GB · Mac Studio M4 MaxQ4_K_M · 8.3 GB · ~61 tok/s · 40KMacs →

Alternatives to MiniCPM O 4 5

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Specifications

Publisher
OpenBMB
Family
MiniCPM
Parameters
9.4B
Architecture
MiniCPMO
Context Length
40,960 tokens
Vocabulary Size
151,748
Release Date
2026-02-03
License
Apache 2.0

Frequently Asked Questions

How much VRAM does MiniCPM O 4 5 need?

MiniCPM O 4 5 requires 6.2 GB of VRAM at Q4_K_M, or 19.4 GB at BF16. Full 41K context adds up to 5.7 GB (12.0 GB total).

VRAM = Weights + KV Cache + Overhead

Weights = 9.4B × 4.8 bits ÷ 8 = 5.6 GB

KV Cache + Overhead ≈ 0.6 GB (at 2K context + ~0.3 GB framework)

Fit ratings and hardware model lists check this model with room for a 16K-token context, which needs a little more memory.

KV Cache + Overhead ≈ 6.4 GB (at full 41K context)

VRAM usage by quantization

6.2 GB
12.0 GB

Learn more about VRAM estimation →

What's the best quantization for MiniCPM O 4 5?

For MiniCPM O 4 5, Q4_K_M (6.2 GB) offers the best balance of quality and VRAM usage. Q5_0 (6.5 GB) provides better quality if you have the VRAM. The smallest option is Q2_K at 4.6 GB.

VRAM requirement by quantization

Q2_K
4.6 GB
Q4_K_S
5.9 GB
Q4_K_M ★
6.2 GB
Q5_0
6.5 GB
Q5_K_M
7.3 GB
BF16
19.4 GB

★ Recommended — best balance of quality and VRAM usage.

Learn more about quantization →

Can I run MiniCPM O 4 5 on a Mac?

Yes — Mac Mini M2 Pro (16 GB) and 133 other Macs can run MiniCPM O 4 5. Apple Silicon uses unified memory, so the model shares RAM with the system. At Q4_K_M you need at least 6.2 GB of usable unified memory (RAM minus macOS overhead).

Can I run MiniCPM O 4 5 locally?

Yes — MiniCPM O 4 5 can run locally on consumer hardware. Popular tools include Ollama, LM Studio, and llama.cpp.

How fast is MiniCPM O 4 5?

At Q4_K_M, MiniCPM O 4 5 can reach ~771 tok/s on AMD Instinct MI350X. On NVIDIA GeForce RTX 4090: ~105 tok/s. Speed depends mainly on GPU memory bandwidth. Real-world results typically within ±20%.

tok/s = (bandwidth GB/s ÷ model GB) × efficiency

Example: NVIDIA B200 → 8000 ÷ 6.23 × 0.65 = ~835 tok/s

Estimated speed at Q4_K_M (6.2 GB)

~835 tok/s
~105 tok/s
~835 tok/s
~771 tok/s

Real-world results typically within ±20%. Speed depends on batch size, quantization kernel, and software stack.

Learn more about tok/s estimation →

What's the download size of MiniCPM O 4 5?

At Q4_K_M, the download is about 5.62 GB. The full-precision BF16 version is 18.74 GB. The smallest option (Q2_K) is 3.98 GB.

Which GPUs can run MiniCPM O 4 5?

52 consumer GPUs can run MiniCPM O 4 5 at Q4_K_M. Top options include AMD Radeon RX 6700 XT, AMD Radeon RX 6800, AMD Radeon RX 6800 XT, AMD Radeon RX 7600. 40 GPUs have plenty of headroom for comfortable inference.

Which devices can run MiniCPM O 4 5?

151 devices with unified memory can run MiniCPM O 4 5 at Q4_K_M (6.2 GB), including AMD Ryzen AI 9 HX 370 (Strix Point) Laptop, ASUS Ascent GX10, Beelink GTR9 Pro (Ryzen AI Max+ 395, 128 GB), Framework Desktop (Ryzen AI Max+ 395, 128 GB). Apple Silicon Macs use unified memory shared between CPU and GPU, making them well-suited for local LLM inference.