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Opus Therapy 9B — Hardware Requirements & GPU Compatibility

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Opus Therapy 9B is a 9B-parameter open language model from Verdugie. At Q4_K_M it needs about 5.94 GB of VRAM — see which GPUs and Macs can run it below.

9B params · denseApache 2.0182 downloads2 likes
Based on Qwen3.5 9B
S

Runs great on a 24 GB GPU

Runs from8 GB Q4_K_M · 8KBest on24 GB Q4_K_M · ~110 tok/s · 32KMacs from16 GB Q4_K_M · ~24 tok/s

Apache 2.0

Reference GPU · RTX 4090 24 GB

Estimates, ±20% · how we estimate

Run Opus Therapy 9B

One recommended way. Every other method, OS and quant is in the step-by-step guide.Each way opens a step-by-step guide for your OS and quant.

Recommended

vLLM
one command · needs vLLM installed
$vllm serve Verdugie/Opus-Therapy-9B --max-model-len 16384

vLLM repo with its own quantisation

Download: Weights on Hugging Face

install, OS, other quants

Ways to runOther ways

each opens step-by-step

Run in cloud

Runs on RTX 3080 Ti (12 GB) (3 GB headroom) · Q4_K_M

Generation speed
~100 tok/s
generation speed
Cost per 1M output tokens
$0.34
per 1M output tokens

How Much VRAM Does Opus Therapy 9B Need?

Select a quantization level; the listed hardware adheres to it.

QuantizationVRAM+32KOn RTX 4090 (reference)
4.2 GB9.9 GB2-bit · K-quant — 2-bit quantization with K-quant improvementsFits: 32K context · ~156 tok/s
4.8 GB10.5 GB3-bit medium — 3-bit medium quantizationFits: 32K context · ~136 tok/s
5.9 GB11.6 GB4-bit medium — 4-bit medium quantization — most popular sweet spotFits: 32K context · ~110 tok/s
7.0 GB12.7 GB5-bit medium — 5-bit medium quantization — good quality/size tradeoffFits: 32K context · ~93 tok/s
8.2 GB13.9 GB6-bit, very good — 6-bit quantization, very good qualityFits: 32K context · ~80 tok/s
9.9 GB15.6 GB8-bit, near-lossless — 8-bit quantization, near-losslessFits: 32K context · ~66 tok/s
19.8 GB25.5 GB16-bit · bfloat — Brain floating point 16 — preferred for trainingFits: 16K context · ~33 tok/s
est.calculated, no published file yet

Selected Q4_K_M

4-bit medium quantization

8.6GBat 16K context

Weights
5.3 GB
KV cache
3.0 GB
Overhead
0.3 GB

Fits RTX 4090 (reference) · 15.4 GB free · ~110 tok/s

≥50 tok/s needs ≥456 GB/s · RTX 5090 ~196, RTX 3090 Ti ~110

Which Hardware Can Run Opus Therapy 9B?

Q4_K_M · 5.9 GB

Opus Therapy 9B (Q4_K_M) requires 5.9 GB of VRAM to load the model weights. For comfortable inference with headroom for KV cache and system overhead, 8+ GB is recommended. 52 GPUs can run it, including NVIDIA GeForce RTX 5090, NVIDIA GeForce RTX 3090 Ti, NVIDIA GeForce RTX 3070 Ti. 151 devices with unified memory can run Opus Therapy 9B, including Mac Studio (M3 Ultra, 256GB), Mac Studio (M3 Ultra, 512GB), NVIDIA Jetson Orin Nano 8GB (Super).

By VRAM tier · typical GPUs and Macs at Q4_K_M
8 GB · RTX 4060Q4_K_M · 8.6 GB · ~30 tok/s · 8Ktight8 GB tier →
12 GB · RTX 3060 12GBQ4_K_M · 8.6 GB · ~39 tok/s · 32K12 GB tier →
16 GB · RTX 5060 Ti 16GBQ4_K_M · 8.6 GB · ~49 tok/s · 32K16 GB tier →
24 GB · RTX 4090referenceQ4_K_M · 8.6 GB · ~110 tok/s · 32K24 GB tier →
Mac 32 GB · Mac Mini M4Q4_K_M · 8.6 GB · ~14 tok/s · 32KMacs →
Mac 64 GB · Mac Studio M4 MaxQ4_K_M · 8.6 GB · ~64 tok/s · 32KMacs →

Alternatives to Opus Therapy 9B

Similar models

6
ModelScoreVRAMtok/sWhy it is similar
Qwen3.5 9BAlibaba99.46.6 GB~103same size
Granite Switch 4.1 8BIBM—8.4 GB~111same size
Ornith 1.5 9Bornith-ai—6.6 GB~103same size
Apertus V1.5 8Bswiss-ai—8.5 GB~111same size
LFM2.5 8B A1BLiquid AI—5.6 GB~335same size
MiniCPM O 4 5OpenBMB—8.3 GB~105same size

Specifications

Publisher
Verdugie
Parameters
9B
Release Date
2026-06-09
License
Apache 2.0

Frequently Asked Questions

How much VRAM does Opus Therapy 9B need?

Opus Therapy 9B requires 5.9 GB of VRAM at Q4_K_M, or 19.8 GB at BF16.

VRAM = Weights + KV Cache + Overhead

Weights = 9B × 4.8 bits ÷ 8 = 5.4 GB

KV Cache + Overhead ≈ 0.5 GB (at 2K context + ~0.3 GB framework)

Fit ratings and hardware model lists check this model with room for a 16K-token context, which needs a little more memory.

VRAM usage by quantization

5.9 GB

Learn more about VRAM estimation →

What's the best quantization for Opus Therapy 9B?

For Opus Therapy 9B, Q4_K_M (5.9 GB) offers the best balance of quality and VRAM usage. Q5_K_M (7.0 GB) provides better quality if you have the VRAM. The smallest option is Q2_K at 4.2 GB.

VRAM requirement by quantization

Q2_K
4.2 GB
Q4_K_M ★
5.9 GB
Q5_K_M
7.0 GB
Q6_K
8.2 GB
Q8_0
9.9 GB
BF16
19.8 GB

★ Recommended — best balance of quality and VRAM usage.

Learn more about quantization →

Can I run Opus Therapy 9B on a Mac?

Yes — Mac Mini M2 Pro (16 GB) and 133 other Macs can run Opus Therapy 9B. Apple Silicon uses unified memory, so the model shares RAM with the system. At Q4_K_M you need at least 5.9 GB of usable unified memory (RAM minus macOS overhead).

Can I run Opus Therapy 9B locally?

Yes — Opus Therapy 9B can run locally on consumer hardware. Popular tools include Ollama, LM Studio, and llama.cpp.

How fast is Opus Therapy 9B?

At Q4_K_M, Opus Therapy 9B can reach ~808 tok/s on AMD Instinct MI350X. On NVIDIA GeForce RTX 4090: ~110 tok/s. Speed depends mainly on GPU memory bandwidth. Real-world results typically within ±20%.

tok/s = (bandwidth GB/s ÷ model GB) × efficiency

Example: NVIDIA B200 → 8000 ÷ 5.94 × 0.65 = ~875 tok/s

Estimated speed at Q4_K_M (5.9 GB)

~875 tok/s
~110 tok/s
~875 tok/s
~808 tok/s

Real-world results typically within ±20%. Speed depends on batch size, quantization kernel, and software stack.

Learn more about tok/s estimation →

What's the download size of Opus Therapy 9B?

At Q4_K_M, the download is about 5.40 GB. The full-precision BF16 version is 18.00 GB. The smallest option (Q2_K) is 3.83 GB.

Which GPUs can run Opus Therapy 9B?

52 consumer GPUs can run Opus Therapy 9B at Q4_K_M. Top options include AMD Radeon RX 6700 XT, AMD Radeon RX 6800, AMD Radeon RX 6800 XT, AMD Radeon RX 7600. 40 GPUs have plenty of headroom for comfortable inference.

Which devices can run Opus Therapy 9B?

151 devices with unified memory can run Opus Therapy 9B at Q4_K_M (5.9 GB), including AMD Ryzen AI 9 HX 370 (Strix Point) Laptop, ASUS Ascent GX10, Beelink GTR9 Pro (Ryzen AI Max+ 395, 128 GB), Framework Desktop (Ryzen AI Max+ 395, 128 GB). Apple Silicon Macs use unified memory shared between CPU and GPU, making them well-suited for local LLM inference.