llmrun

Llama 4 Scout 17B 16E Instruct vs Mistral Large Instruct 2407

Llama 4 Scout 17B 16E Instruct and Mistral Large Instruct 2407 match in llmrun Score, with values of 81.8 versus 81.1; neither fits 24 GB.

108.6B · 17B active · Other · Apr 2025

Vision

122.6B · Other · Jul 2024

ChatFunctions

Which should you choose?

Choose Llama 4 Scout 17B 16E Instruct if you want…

  • Ahead on the benchmarks

    4 of 6 shared boards

  • Fits a Mac 64 GB

    IQ3_M · 59.1 GB; Mistral Large Instruct 2407 needs 42.6 GB at its smallest quant

  • Also does vision

    Mistral Large Instruct 2407 doesn't list it

  • Newer release

    Apr 2025 vs Jul 2024

Choose Mistral Large Instruct 2407 if you want…

  • Also does chat, function-calling

    Llama 4 Scout 17B 16E Instruct doesn't list it

On your hardware

Each model at its default quant (Q4_K_M), a smaller one when it must. Estimates, ±20%.

8 GB

RTX 4060 · 8 GB tier

Llama 4 Scout 17B 16E Instruct

Doesn't fit

smallest quant needs 38.2 GB

Mistral Large Instruct 2407

Doesn't fit

smallest quant needs 42.6 GB

12 GB

RTX 3060 12GB · 12 GB tier

Llama 4 Scout 17B 16E Instruct

Doesn't fit

smallest quant needs 38.2 GB

Mistral Large Instruct 2407

Doesn't fit

smallest quant needs 42.6 GB

16 GB

RTX 5060 Ti 16GB · 16 GB tier

Llama 4 Scout 17B 16E Instruct

Doesn't fit

smallest quant needs 38.2 GB

Mistral Large Instruct 2407

Doesn't fit

smallest quant needs 42.6 GB

24 GBreference

RTX 4090 · 24 GB tier

Llama 4 Scout 17B 16E Instruct

Doesn't fit

smallest quant needs 38.2 GB

Mistral Large Instruct 2407

Doesn't fit

smallest quant needs 42.6 GB

32 GB

RTX 5090 · 32 GB tier

Llama 4 Scout 17B 16E Instruct

Doesn't fit

smallest quant needs 38.2 GB

Mistral Large Instruct 2407

Doesn't fit

smallest quant needs 42.6 GB

48 GB

RTX A6000 · 48 GB tier

Llama 4 Scout 17B 16E Instruct

IQ2_M · ~65 tok/s

45.7 GB · up to 16K

Mistral Large Instruct 2407

IQ2_S · ~12 tok/s

47.7 GB · up to 16K

Mac 32 GB

Mac Mini M4 · Macs

Llama 4 Scout 17B 16E Instruct

Doesn't fit

smallest quant needs 38.2 GB

Mistral Large Instruct 2407

Doesn't fit

smallest quant needs 42.6 GB

Mac 64 GB

Mac Studio M4 Max · Macs

Llama 4 Scout 17B 16E Instruct

IQ3_M · ~32 tok/s

59.1 GB · up to 16Kbetter quant

Mistral Large Instruct 2407

Q2_K_S · ~7 tok/s

59.5 GB · up to 16K

Mac 128 GB

Mac Studio M4 Max · Macs

Llama 4 Scout 17B 16E Instruct

Q4_K_M · ~26 tok/s

77 GB · up to 32Kfaster

Mistral Large Instruct 2407

Q4_K_M · ~5 tok/s

86.4 GB · up to 32K

Reference GPU: RTX 4090. Tinted cell = the better pick on that machine (fits, more headroom, or at least 10% faster).

llmrun Score

with its 90% range · bars share one scale

Overall

Llama 4 Scout 17B 16E Instruct

81.878–86

Mistral Large Instruct 2407

81.177–86

Science

Llama 4 Scout 17B 16E Instruct

83.075–91

Mistral Large Instruct 2407

no data

Reasoning

Llama 4 Scout 17B 16E Instruct

79.770–89

Mistral Large Instruct 2407

83.175–92

Llama 4 Scout 17B 16E Instruct · #79 of 100 open models · #40 of 60 that fit ≤96 GB

Mistral Large Instruct 2407 · #81 of 100 open models · #42 of 60 that fit ≤96 GB

Benchmarks

6 shared boards: Llama 4 Scout 17B 16E Instruct leads 4, Mistral Large Instruct 2407 leads 2 · Benchmarks imported Oct 2026

Llama 4 Scout 17B 16E Instruct

51.8%#51/98 open

IndependentEpoch AI · Apr 2025

Mistral Large Instruct 2407

49.0%#56/98 open

IndependentEpoch AI · Jul 2024

Llama 4 Scout 17B 16E Instruct

7.8%#62/86 open

IndependentEpoch AI · Apr 2025

Mistral Large Instruct 2407

8.5%#59/86 open

IndependentEpoch AI · Jul 2024

Llama 4 Scout 17B 16E Instruct

74.3%#31/145 open

IndependentTIGER-Lab

Mistral Large Instruct 2407

65.9%#45/145 open

IndependentTIGER-Lab

Llama 4 Scout 17B 16E Instruct

62.3%#12/39 open

IndependentEpoch AI · Apr 2025

Mistral Large Instruct 2407

44.8%#17/39 open

IndependentEpoch AI · Jul 2024

Llama 4 Scout 17B 16E Instruct

57.9%#53/68 open

Lab-reportedEpoch AI · Apr 2025

Mistral Large Instruct 2407

61.2%#45/68 open

Lab-reportedEpoch AI · Jul 2024

Llama 4 Scout 17B 16E Instruct

57.5#17/26 open

Lab-reportedEpoch AI · Apr 2025

Mistral Large Instruct 2407

57.1#20/26 open

Lab-reportedEpoch AI · Jul 2024

9 more boards (other shared and single-model boards)

Llama 4 Scout 17B 16E Instruct

1321.5#94/187 open

ArenaLMArena · Oct 2026

Mistral Large Instruct 2407

1314.4#98/187 open

ArenaLMArena · Oct 2026

Only Llama 4 Scout 17B 16E Instruct (6)

Only Mistral Large Instruct 2407 (2)

VRAM by quantization

Memory to load the model and 2K context; below it, the total at 32K and 128K context. Lighter side in bold.

Q2_K

Llama 4 Scout 17B 16E Instruct

50.8 GB39.6 GB file

32K 62.2 GB · 128K 98.7 GB

Mistral Large Instruct 2407

57.3 GB45.2 GB file

32K 69.1 GB · 128K 107 GB

Q3_K_S

Llama 4 Scout 17B 16E Instruct

52.3 GB46.7 GB file

32K 63.7 GB · 128K 100 GB

Mistral Large Instruct 2407

59.0 GB52.8 GB file

32K 70.8 GB · 128K 109 GB

Q3_K_M

Llama 4 Scout 17B 16E Instruct

58.3 GB51.8 GB file

32K 69.7 GB · 128K 106 GB

Mistral Large Instruct 2407

65.8 GB59.1 GB file

32K 77.6 GB · 128K 115 GB

Q4_0

Llama 4 Scout 17B 16E Instruct

59.8 GB61.2 GB file

32K 71.2 GB · 128K 108 GB

Mistral Large Instruct 2407

67.4 GB69.1 GB file

32K 79.3 GB · 128K 117 GB

Q4_K_M

Llama 4 Scout 17B 16E Instruct

71.7 GB65.4 GB file

32K 83.1 GB · 128K 120 GB

Mistral Large Instruct 2407

80.9 GB73.2 GB file

32K 92.7 GB · 128K 131 GB

Q5_K_M

Llama 4 Scout 17B 16E Instruct

85.2 GB76.5 GB file

32K 96.6 GB · 128K 133 GB

Mistral Large Instruct 2407

96.1 GB86.5 GB file

32K 108 GB · 128K 146 GB

Q6_K

Llama 4 Scout 17B 16E Instruct

98.6 GB88.4 GB file

32K 110 GB · 128K 147 GB

Mistral Large Instruct 2407

111 GB100.6 GB file

32K 123 GB · 128K 161 GB

Q8_0

Llama 4 Scout 17B 16E Instruct

120 GB114.5 GB file

32K 131 GB · 128K 167 GB

Mistral Large Instruct 2407

135 GB130.3 GB file

32K 147 GB · 128K 184 GB

17 more quants

IQ2_XXS

Llama 4 Scout 17B 16E Instruct

32.9 GB37.4 GB file

32K 44.3 GB · 128K 80.8 GB

Mistral Large Instruct 2407

37.1 GB32.4 GB file

32K 48.9 GB · 128K 86.7 GB

IQ2_XS

Llama 4 Scout 17B 16E Instruct

35.9 GB31.8 GB file

32K 47.3 GB · 128K 83.8 GB

Mistral Large Instruct 2407

40.5 GB36.1 GB file

32K 52.3 GB · 128K 90.1 GB

IQ2_S

Llama 4 Scout 17B 16E Instruct

37.4 GB32.3 GB file

32K 48.8 GB · 128K 85.3 GB

Mistral Large Instruct 2407

42.2 GB38.4 GB file

32K 54.0 GB · 128K 91.8 GB

IQ2_M

Llama 4 Scout 17B 16E Instruct

40.3 GB39.1 GB file

32K 51.8 GB · 128K 88.3 GB

Mistral Large Instruct 2407

45.5 GB41.6 GB file

32K 57.3 GB · 128K 95.1 GB

IQ3_XXS

Llama 4 Scout 17B 16E Instruct

46.3 GB45.7 GB file

32K 57.7 GB · 128K 94.3 GB

Mistral Large Instruct 2407

52.3 GB47.0 GB file

32K 64.1 GB · 128K 102 GB

Q2_K_S

Llama 4 Scout 17B 16E Instruct

47.8 GB37.0 GB file

32K 59.2 GB · 128K 95.8 GB

Mistral Large Instruct 2407

54.0 GB41.6 GB file

32K 65.8 GB · 128K 104 GB

IQ3_XS

Llama 4 Scout 17B 16E Instruct

49.3 GB44.3 GB file

32K 60.7 GB · 128K 97.3 GB

Mistral Large Instruct 2407

55.6 GB50.1 GB file

32K 67.4 GB · 128K 105 GB

IQ3_S

Llama 4 Scout 17B 16E Instruct

50.8 GB46.8 GB file

32K 62.2 GB · 128K 98.7 GB

Mistral Large Instruct 2407

not listed

IQ3_M

Llama 4 Scout 17B 16E Instruct

53.8 GB47.5 GB file

32K 65.2 GB · 128K 102 GB

Mistral Large Instruct 2407

60.7 GB55.3 GB file

32K 72.5 GB · 128K 110 GB

Q3_K_L

Llama 4 Scout 17B 16E Instruct

61.3 GB57.8 GB file

32K 72.7 GB · 128K 109 GB

Mistral Large Instruct 2407

69.1 GB64.6 GB file

32K 80.9 GB · 128K 119 GB

IQ4_XS

Llama 4 Scout 17B 16E Instruct

64.2 GB57.7 GB file

32K 75.7 GB · 128K 112 GB

Mistral Large Instruct 2407

72.5 GB65.4 GB file

32K 84.3 GB · 128K 122 GB

IQ4_NL

Llama 4 Scout 17B 16E Instruct

67.2 GB60.9 GB file

32K 78.6 GB · 128K 115 GB

Mistral Large Instruct 2407

not listed

Q4_1

Llama 4 Scout 17B 16E Instruct

67.2 GB67.6 GB file

32K 78.6 GB · 128K 115 GB

Mistral Large Instruct 2407

not listed

Q4_K_S

Llama 4 Scout 17B 16E Instruct

67.2 GB61.5 GB file

32K 78.6 GB · 128K 115 GB

Mistral Large Instruct 2407

75.9 GB69.6 GB file

32K 87.7 GB · 128K 125 GB

Q5_0

Llama 4 Scout 17B 16E Instruct

not listed

Mistral Large Instruct 2407

84.3 GB84.4 GB file

32K 96.1 GB · 128K 134 GB

Q5_K_S

Llama 4 Scout 17B 16E Instruct

82.2 GB74.3 GB file

32K 93.6 GB · 128K 130 GB

Mistral Large Instruct 2407

92.7 GB84.4 GB file

32K 105 GB · 128K 142 GB

BF16

Llama 4 Scout 17B 16E Instruct

239 GB215.6 GB file

32K 250 GB · 128K 287 GB

Mistral Large Instruct 2407

270 GB~245.2 GB file

32K 282 GB · 128K 319 GB

How to run each

Specifications

Specifications of Llama 4 Scout 17B 16E Instruct and Mistral Large Instruct 2407
SpecLlama 4 Scout 17B 16E InstructMistral Large Instruct 2407
PublisherMetaMistral AI
Parameters108.6B122.6B
Active parameters17B per token—
ModalitiesVisionChat, Function-calling
LicenseOtherOther
ReleasedApr 2025Jul 2024

Frequently Asked Questions

Which is better, Llama 4 Scout 17B 16E Instruct or Mistral Large Instruct 2407?

Llama 4 Scout 17B 16E Instruct and Mistral Large Instruct 2407 match in llmrun Score, with values of 81.8 versus 81.1; neither fits 24 GB. Choose Llama 4 Scout 17B 16E Instruct for ahead on the benchmarks and fits a Mac 64 GB; choose Mistral Large Instruct 2407 for also does chat, function-calling.

Which needs less VRAM, Llama 4 Scout 17B 16E Instruct or Mistral Large Instruct 2407?

At Q4_K_M, Llama 4 Scout 17B 16E Instruct requires 71.7 GB while Mistral Large Instruct 2407 needs 80.9 GB, making Llama 4 Scout 17B 16E Instruct the easier model to run on your local setup.

Can I run Llama 4 Scout 17B 16E Instruct or Mistral Large Instruct 2407 on a 16 GB GPU?

Llama 4 Scout 17B 16E Instruct does not fit (smallest quant needs 38.2 GB); Mistral Large Instruct 2407 does not fit (smallest quant needs 42.6 GB).

Llama 4 Scout 17B 16E Instruct vs Mistral Large Instruct 2407 — VRAM & GPU Comparison | llmrun