llmrun

Llama 4 Scout 17B 16E Instruct vs Qwen2.5 72B Instruct

Llama 4 Scout 17B 16E Instruct and Qwen2.5 72B Instruct match in llmrun Score, with values of 81.8 versus 81.7; neither fits 24 GB.

108.6B · 17B active · Other · Apr 2025

Vision

72.7B · 32K context · Other · Sep 2024

ChatFunctions

Which should you choose?

Choose Llama 4 Scout 17B 16E Instruct if you want…

  • Also does vision

    Qwen2.5 72B Instruct doesn't list it

  • Newer release

    Apr 2025 vs Sep 2024

Choose Qwen2.5 72B Instruct if you want…

  • Fits a 48 GB GPU

    Q4_K_M · 49.3 GB; Llama 4 Scout 17B 16E Instruct needs 38.2 GB at its smallest quant

  • Lighter on memory

    44.6 vs 71.7 GB at Q4_K_M

  • Also does chat, function-calling

    Llama 4 Scout 17B 16E Instruct doesn't list it

On your hardware

Each model at its default quant (Q4_K_M), a smaller one when it must. Estimates, ±20%.

8 GB

RTX 4060 · 8 GB tier

Llama 4 Scout 17B 16E Instruct

Doesn't fit

smallest quant needs 38.2 GB

Qwen2.5 72B Instruct

Doesn't fit

smallest quant needs 25.7 GB

12 GB

RTX 3060 12GB · 12 GB tier

Llama 4 Scout 17B 16E Instruct

Doesn't fit

smallest quant needs 38.2 GB

Qwen2.5 72B Instruct

Doesn't fit

smallest quant needs 25.7 GB

16 GB

RTX 5060 Ti 16GB · 16 GB tier

Llama 4 Scout 17B 16E Instruct

Doesn't fit

smallest quant needs 38.2 GB

Qwen2.5 72B Instruct

Doesn't fit

smallest quant needs 25.7 GB

24 GBreference

RTX 4090 · 24 GB tier

Llama 4 Scout 17B 16E Instruct

Doesn't fit

smallest quant needs 38.2 GB

Qwen2.5 72B Instruct

Doesn't fit

smallest quant needs 25.7 GB

32 GB

RTX 5090 · 32 GB tier

Llama 4 Scout 17B 16E Instruct

Doesn't fit

smallest quant needs 38.2 GB

Qwen2.5 72B Instruct

IQ2_M · ~46 tok/s

30.2 GB · up to 16Kfits

48 GB

RTX A6000 · 48 GB tier

Llama 4 Scout 17B 16E Instruct

IQ2_M · ~65 tok/s

45.7 GB · up to 16Kmore headroom

Qwen2.5 72B Instruct

Q4_K_M · ~11 tok/stight

49.3 GB · up to 8K

Mac 32 GB

Mac Mini M4 · Macs

Llama 4 Scout 17B 16E Instruct

Doesn't fit

smallest quant needs 38.2 GB

Qwen2.5 72B Instruct

IQ2_S · ~4 tok/s

28.4 GB · up to 16Kfits

Mac 64 GB

Mac Studio M4 Max · Macs

Llama 4 Scout 17B 16E Instruct

IQ3_M · ~32 tok/s

59.1 GB · up to 16K

Qwen2.5 72B Instruct

Q4_K_M · ~9 tok/s

49.3 GB · up to 32Kmore headroom

Mac 128 GB

Mac Studio M4 Max · Macs

Llama 4 Scout 17B 16E Instruct

Q4_K_M · ~26 tok/s

77 GB · up to 32Kfaster

Qwen2.5 72B Instruct

Q4_K_M · ~9 tok/s

49.3 GB · up to 32K

Reference GPU: RTX 4090. Tinted cell = the better pick on that machine (fits, more headroom, or at least 10% faster).

llmrun Score

with its 90% range · bars share one scale

Overall

Llama 4 Scout 17B 16E Instruct

81.878–86

Qwen2.5 72B Instruct

81.777–86

Science

Llama 4 Scout 17B 16E Instruct

83.075–91

Qwen2.5 72B Instruct

no data

Reasoning

Llama 4 Scout 17B 16E Instruct

79.770–89

Qwen2.5 72B Instruct

85.677–94

Llama 4 Scout 17B 16E Instruct · #79 of 100 open models · #40 of 60 that fit ≤96 GB

Qwen2.5 72B Instruct · #80 of 100 open models · #30 of 49 that fit ≤64 GB

Benchmarks

7 shared boards: Llama 4 Scout 17B 16E Instruct leads 2, Qwen2.5 72B Instruct leads 4 · Benchmarks imported Oct 2026

Llama 4 Scout 17B 16E Instruct

51.8%#51/98 open

IndependentEpoch AI · Apr 2025

Qwen2.5 72B Instruct

49.1%#54/98 open

IndependentEpoch AI · Sep 2024

Llama 4 Scout 17B 16E Instruct

7.8%#62/86 open

IndependentEpoch AI · Apr 2025

Qwen2.5 72B Instruct

8.1%#60/86 open

IndependentEpoch AI · Sep 2024

Llama 4 Scout 17B 16E Instruct

74.3%#31/145 open

IndependentTIGER-Lab

Qwen2.5 72B Instruct

71.6%#35/145 open

IndependentTIGER-Lab

Llama 4 Scout 17B 16E Instruct

62.3%#12/39 open

IndependentEpoch AI · Apr 2025

Qwen2.5 72B Instruct

63.2%#11/39 open

IndependentEpoch AI · Sep 2024

Llama 4 Scout 17B 16E Instruct

57.9%#53/68 open

Lab-reportedEpoch AI · Apr 2025

Qwen2.5 72B Instruct

62.9%#40/68 open

Lab-reportedEpoch AI · Sep 2024

Llama 4 Scout 17B 16E Instruct

57.5#17/26 open

Lab-reportedEpoch AI · Apr 2025

Qwen2.5 72B Instruct

57.5#18/26 open

Lab-reportedEpoch AI · Sep 2024

Llama 4 Scout 17B 16E Instruct

12.0%#46/54 open

Lab-reportedEpoch AI · Apr 2025

Qwen2.5 72B Instruct

13.4%#44/54 open

Lab-reportedEpoch AI · Sep 2024

10 more boards (other shared and single-model boards)

Llama 4 Scout 17B 16E Instruct

1321.5#94/187 open

ArenaLMArena · Oct 2026

Qwen2.5 72B Instruct

1302.9#106/187 open

ArenaLMArena · Oct 2026

Only Llama 4 Scout 17B 16E Instruct (5)

Only Qwen2.5 72B Instruct (4)

VRAM by quantization

Memory to load the model and 2K context; below it, the total at 32K and 128K context. Lighter side in bold.

Q2_K

Llama 4 Scout 17B 16E Instruct

50.8 GB39.6 GB file

32K 62.2 GB · 128K 98.7 GB

Qwen2.5 72B Instruct

31.9 GB29.8 GB file

32K 41.9 GB · 128K —

Q3_K_S

Llama 4 Scout 17B 16E Instruct

52.3 GB46.7 GB file

32K 63.7 GB · 128K 100 GB

Qwen2.5 72B Instruct

32.8 GB34.5 GB file

32K 42.9 GB · 128K —

Q3_K_M

Llama 4 Scout 17B 16E Instruct

58.3 GB51.8 GB file

32K 69.7 GB · 128K 106 GB

Qwen2.5 72B Instruct

36.4 GB37.7 GB file

32K 46.5 GB · 128K —

Q4_0

Llama 4 Scout 17B 16E Instruct

59.8 GB61.2 GB file

32K 71.2 GB · 128K 108 GB

Qwen2.5 72B Instruct

37.3 GB41.4 GB file

32K 47.4 GB · 128K —

Q4_K_M

Llama 4 Scout 17B 16E Instruct

71.7 GB65.4 GB file

32K 83.1 GB · 128K 120 GB

Qwen2.5 72B Instruct

44.6 GB47.4 GB file

32K 54.7 GB · 128K —

Q5_K_M

Llama 4 Scout 17B 16E Instruct

85.2 GB76.5 GB file

32K 96.6 GB · 128K 133 GB

Qwen2.5 72B Instruct

52.8 GB54.4 GB file

32K 62.8 GB · 128K —

Q6_K

Llama 4 Scout 17B 16E Instruct

98.6 GB88.4 GB file

32K 110 GB · 128K 147 GB

Qwen2.5 72B Instruct

61.0 GB64.3 GB file

32K 71.0 GB · 128K —

Q8_0

Llama 4 Scout 17B 16E Instruct

120 GB114.5 GB file

32K 131 GB · 128K 167 GB

Qwen2.5 72B Instruct

73.7 GB77.3 GB file

32K 83.8 GB · 128K —

17 more quants

IQ2_XXS

Llama 4 Scout 17B 16E Instruct

32.9 GB37.4 GB file

32K 44.3 GB · 128K 80.8 GB

Qwen2.5 72B Instruct

21.0 GB25.5 GB file

32K 31.0 GB · 128K —

IQ2_XS

Llama 4 Scout 17B 16E Instruct

35.9 GB31.8 GB file

32K 47.3 GB · 128K 83.8 GB

Qwen2.5 72B Instruct

22.8 GB27.1 GB file

32K 32.9 GB · 128K —

IQ2_S

Llama 4 Scout 17B 16E Instruct

37.4 GB32.3 GB file

32K 48.8 GB · 128K 85.3 GB

Qwen2.5 72B Instruct

23.7 GB27.9 GB file

32K 33.8 GB · 128K —

IQ2_M

Llama 4 Scout 17B 16E Instruct

40.3 GB39.1 GB file

32K 51.8 GB · 128K 88.3 GB

Qwen2.5 72B Instruct

25.5 GB29.3 GB file

32K 35.6 GB · 128K —

IQ3_XXS

Llama 4 Scout 17B 16E Instruct

46.3 GB45.7 GB file

32K 57.7 GB · 128K 94.3 GB

Qwen2.5 72B Instruct

29.1 GB31.8 GB file

32K 39.2 GB · 128K —

Q2_K_S

Llama 4 Scout 17B 16E Instruct

47.8 GB37.0 GB file

32K 59.2 GB · 128K 95.8 GB

Qwen2.5 72B Instruct

30.1 GB29.6 GB file

32K 40.1 GB · 128K —

IQ3_XS

Llama 4 Scout 17B 16E Instruct

49.3 GB44.3 GB file

32K 60.7 GB · 128K 97.3 GB

Qwen2.5 72B Instruct

31.0 GB32.8 GB file

32K 41.0 GB · 128K —

IQ3_S

Llama 4 Scout 17B 16E Instruct

50.8 GB46.8 GB file

32K 62.2 GB · 128K 98.7 GB

Qwen2.5 72B Instruct

31.9 GB34.5 GB file

32K 41.9 GB · 128K —

IQ3_M

Llama 4 Scout 17B 16E Instruct

53.8 GB47.5 GB file

32K 65.2 GB · 128K 102 GB

Qwen2.5 72B Instruct

33.7 GB35.5 GB file

32K 43.8 GB · 128K —

Q3_K_L

Llama 4 Scout 17B 16E Instruct

61.3 GB57.8 GB file

32K 72.7 GB · 128K 109 GB

Qwen2.5 72B Instruct

38.2 GB39.5 GB file

32K 48.3 GB · 128K —

IQ4_XS

Llama 4 Scout 17B 16E Instruct

64.2 GB57.7 GB file

32K 75.7 GB · 128K 112 GB

Qwen2.5 72B Instruct

40.1 GB39.7 GB file

32K 50.1 GB · 128K —

IQ4_NL

Llama 4 Scout 17B 16E Instruct

67.2 GB60.9 GB file

32K 78.6 GB · 128K 115 GB

Qwen2.5 72B Instruct

41.9 GB41.3 GB file

32K 51.9 GB · 128K —

Q4_1

Llama 4 Scout 17B 16E Instruct

67.2 GB67.6 GB file

32K 78.6 GB · 128K 115 GB

Qwen2.5 72B Instruct

41.9 GB45.7 GB file

32K 51.9 GB · 128K —

Q4_K_S

Llama 4 Scout 17B 16E Instruct

67.2 GB61.5 GB file

32K 78.6 GB · 128K 115 GB

Qwen2.5 72B Instruct

41.9 GB43.9 GB file

32K 51.9 GB · 128K —

Q5_0

Llama 4 Scout 17B 16E Instruct

not listed

Qwen2.5 72B Instruct

46.4 GB50.3 GB file

32K 56.5 GB · 128K —

Q5_K_S

Llama 4 Scout 17B 16E Instruct

82.2 GB74.3 GB file

32K 93.6 GB · 128K 130 GB

Qwen2.5 72B Instruct

51.0 GB51.4 GB file

32K 61.0 GB · 128K —

BF16

Llama 4 Scout 17B 16E Instruct

239 GB215.6 GB file

32K 250 GB · 128K 287 GB

Qwen2.5 72B Instruct

146 GB~145.4 GB file

32K 156 GB · 128K —

How to run each

Specifications

Specifications of Llama 4 Scout 17B 16E Instruct and Qwen2.5 72B Instruct
SpecLlama 4 Scout 17B 16E InstructQwen2.5 72B Instruct
PublisherMetaAlibaba
Parameters108.6B72.7B
Active parameters17B per token—
Architecture—Qwen2ForCausalLM
Context—32K tokens
ModalitiesVisionChat, Function-calling
LicenseOtherOther
ReleasedApr 2025Sep 2024

Frequently Asked Questions

Which is better, Llama 4 Scout 17B 16E Instruct or Qwen2.5 72B Instruct?

Llama 4 Scout 17B 16E Instruct and Qwen2.5 72B Instruct match in llmrun Score, with values of 81.8 versus 81.7; neither fits 24 GB. Choose Llama 4 Scout 17B 16E Instruct for also does vision and newer release; choose Qwen2.5 72B Instruct for fits a 48 GB GPU and lighter on memory.

Which needs less VRAM, Llama 4 Scout 17B 16E Instruct or Qwen2.5 72B Instruct?

At Q4_K_M, Llama 4 Scout 17B 16E Instruct requires 71.7 GB while Qwen2.5 72B Instruct needs 44.6 GB, making Qwen2.5 72B Instruct the easier model to run on your local setup.

Can I run Llama 4 Scout 17B 16E Instruct or Qwen2.5 72B Instruct on a 16 GB GPU?

Llama 4 Scout 17B 16E Instruct does not fit (smallest quant needs 38.2 GB); Qwen2.5 72B Instruct does not fit (smallest quant needs 25.7 GB).