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Mistral Large 3 675B Instruct 2512 — Hardware Requirements & GPU Compatibility

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Mistral-Large-3-675B-Instruct-2512 is Mistral AI's flagship instruction-tuned model, a multimodal granular Mixture-of-Experts system pairing a roughly 673-billion-parameter, about 39-billion-active-parameter language backbone with a 2.5-billion-parameter vision encoder, for around 675 billion total and 41 billion active parameters overall. It handles vision alongside text, supports dozens of languages, and is built for agentic use with native function calling and JSON output, aimed at long-document understanding, coding, and enterprise knowledge work rather than dedicated step-by-step reasoning. This is a frontier-scale model that requires a full multi-GPU server node to run, even quantized. Context length is 262,144 tokens. It is released under the Apache 2.0 license, permitting unrestricted commercial and research use. It was published in November 2025, as the third generation of Mistral's Large model line, alongside FP8, NVFP4, and BF16 weight releases.

675B params · MoE41B activeApache 2.02.5K downloads261 likes6.6K quant downloads

Mistral Large 3 675B Instruct 2512 runs on a 512 GB+ Mac or a multi-GPU server

Best local pick → Mac Studio (M3 Ultra, 512GB) · Q4_K_M · 454.4 GB · ~18 tok/s

Macs from256 GB IQ2_S · ~29 tok/s

Score 89.6#75 of 106 open#71 of 102 that fit ≤512 GBApache 2.0

Not set up for it?

Reference GPU · RTX 4090 24 GB

Estimates, ±20% · how we estimate

Run Mistral Large 3 675B Instruct 2512

One recommended way. Every other method, OS and quant is in the step-by-step guide.Each way opens a step-by-step guide for your OS and quant.

Recommended

vLLM on a multi-GPU server
tensor + pipeline parallel · needs vLLM on every node
$vllm serve mistralai/Mistral-Large-3-675B-Instruct-2512 --max-model-len 16384 --tensor-parallel-size 8

Size the nodes from the table above

Download: Q4_K_M/Mistral-Large-3-675B-Instruct-2512-Q4_K_M-00001-of-00009.gguf406.99 GB + 8 partsunsloth

install, other ways

Ways to runOther ways

each opens step-by-step

Run in cloud

Rent 7× H100 SXM · Q4_K_M

Estimated hourly price
~$18.83/hr
est., whole server
GPUs
7 GPUs
560 GB of VRAM

How Much VRAM Does Mistral Large 3 675B Instruct 2512 Need?

Select a quantization level; the listed hardware adheres to it.

QuantizationVRAM+32KRuns on
315.6 GB334.6 GB2-bit · K-quant — 2-bit quantization with K-quant improvementsRuns on 5× H100 SXM 80 GB
324.8 GB343.9 GB3-bit small — 3-bit small quantizationRuns on 5× H100 SXM 80 GB
362.0 GB381 GB3-bit medium — 3-bit medium quantizationRuns on 6× H100 SXM 80 GB
371.3 GB390.3 GB4-bit · legacy — 4-bit legacy quantizationRuns on 6× H100 SXM 80 GB
445.5 GB464.5 GB4-bit medium — 4-bit medium quantization — most popular sweet spotRuns on 7× H100 SXM 80 GB
529.0 GB548.1 GB5-bit medium — 5-bit medium quantization — good quality/size tradeoffRuns on 8× H100 SXM 80 GB
612.6 GB631.6 GB6-bit, very good — 6-bit quantization, very good qualityRuns on 5× H200 SXM 141 GB
742.5 GB761.5 GB8-bit, near-lossless — 8-bit quantization, near-losslessRuns on 6× H200 SXM 141 GB

Selected Q4_K_M

4-bit medium quantization

454.4GBat 16K context

Weights
443.9 GB
KV cache
10.2 GB
Overhead
0.3 GB

Server-class: ~454.4 GB at 16K context · about 7× H100 SXM 80 GB

Which Hardware Can Run Mistral Large 3 675B Instruct 2512?

Q4_K_M · 445.5 GB

Mistral Large 3 675B Instruct 2512 (Q4_K_M) requires 445.5 GB of VRAM to load the model weights. For comfortable inference with headroom for KV cache and system overhead, 580+ GB is recommended. No consumer GPU has enough memory. 1 device with unified memory can run Mistral Large 3 675B Instruct 2512, including Mac Studio (M3 Ultra, 512GB).

Needs server-class hardware

Mistral Large 3 675B Instruct 2512 runs on a 512 GB+ Mac or a multi-GPU server · Q4_K_M needs ~454.4 GB

Hardware that runs this model
HardwareQuantMemorySpeedContextHardware page
Mac 256 GB · Mac Studio (M3 Ultra, 256GB)IQ2_S240.9 GB~29 tok/s32K ctxMac Studio →IQ2_S · 240.9 GB · ~29 tok/s · 32K ctx
Mac 512 GB · Mac Studio (M3 Ultra, 512GB)Q4_K_M454.4 GB~18 tok/s32K ctxMac Studio →Q4_K_M · 454.4 GB · ~18 tok/s · 32K ctx
7× H100 SXM 80 GB · 560 GBQ4_K_M454.4 GB—32K ctxH100 SXM →Q4_K_M · 454.4 GB · 32K ctx
4× H200 SXM 141 GB · 564 GBQ4_K_M454.4 GB—32K ctxH200 SXM →Q4_K_M · 454.4 GB · 32K ctx
3× B200 192 GB · 576 GBQ4_K_M454.4 GB—32K ctxB200 →Q4_K_M · 454.4 GB · 32K ctx

Also: Mac Studio (M3 Ultra, 512GB) · NVIDIA DGX A100 640GB · NVIDIA DGX H100

≤ 640 GB tier →

By VRAM tier · typical GPUs and Macs at Q4_K_M

Consumer GPUs (up to 32 GB) and Macs up to 192 GB: too small for this model (needs ≥ 213.1 GB)8 GB tier →12 GB tier →16 GB tier →24 GB tier →Macs →

How good is Mistral Large 3 675B Instruct 2512?

The llmrun Score merges 5 public benchmark boards into a single figure, where 100 represents the average for open models.

Score vs VRAM in the ≤512 GB tier

  • Mistral Large 3 675B Instruct 2512
  • Other models
  • Best Score for its VRAM

#71 of 102 that fit ≤512 GB

Each dot is a model at the best quant that fits ≤512 GB. The line steps up to the best Score available at each amount of VRAM; a dot below it is beaten by a model that needs no more memory.

Full ≤512 GB ranking →

Benchmarks

The 6 boards that weigh most in the llmrun Score, of 7 with a result for this model; badges show who ran the test.

  • LMArena Text

    LMArena · Oct 2026Arena

    1414.3

    #41/188 open

    Arena
  • LMArena WebDev

    LMArena · Oct 2026Arena

    1232.6

    #53/55 open

    Arena
  • SciCode

    Epoch AI · Dec 2025Lab-reported

    36.6%

    #47/72 open

    Lab-reported
  • ALE-Bench

    Epoch AI · Dec 2025Lab-reported

    264.7

    #46/48 open

    Lab-reported
  • CritPt

    Epoch AI · Dec 2025Lab-reported

    0.0%

    #72/84 open

    Lab-reported
  • DTBench

    Epoch AI · Dec 2025Lab-reported

    65.1%

    #39/70 open

    Lab-reported

In the ≤512 GB class

102 models fit ≤512 GB

Same Score, only models that fit ≤512 GB at their best quant: this model's peers by memory need.

  1. #1

    134.4

    458.4 GB

  2. #2

    133.3

    499.3 GB

  3. #3

    131.9

    186.5 GB

  4. #4

    130.1

    453.8 GB

  5. #5

    129.4

    458.4 GB

  6. #6

    128.0

    407.5 GB

Alternatives to Mistral Large 3 675B Instruct 2512

Mistral family · 35 models →

Official models with an llmrun Score, each answering one question; sizes are each model's default quant (usually Q4_K_M) with a 16K-token context.

Similar models

10
ModelScoreVRAMWhy it is similar
DeepSeek V4.1 FlashDeepSeek129.4458.4 GBsimilar score
Step 5 PreviewStepFun128.0407.5 GBsimilar score
GLM 5.2Z.ai122.9453.8 GBsimilar score
Beam 1.0 501B A23Breflection119.5304 GBsimilar score
GLM 5.1Z.ai117.8454.1 GBsimilar score
Qwen3.5 397B A17BAlibaba112.8242.6 GBsimilar score
Qwen3.5 4BAlibaba98.53.4 GBsimilar score
Llama 4 Maverick 17B 128E InstructMeta87.1272.7 GBsimilar score
Llama 3.1 405B InstructMeta83.5275.6 GBsimilar score
GLM 5Z.ai111.8454.1 GBsame size

Specifications

Publisher
Mistral AI
Family
Mistral
Parameters
675B
Active parameters
41B per token
Release Date
2025-11-28
License
Apache 2.0

Frequently Asked Questions

How much VRAM does Mistral Large 3 675B Instruct 2512 need?

Mistral Large 3 675B Instruct 2512 requires 445.5 GB of VRAM at Q4_K_M, or 1485 GB at BF16.

VRAM = Weights + KV Cache + Overhead

Weights = 675B × 4.8 bits ÷ 8 = 405 GB

KV Cache + Overhead ≈ 40.5 GB (at 2K context + ~0.3 GB framework)

Fit ratings and hardware model lists check this model with room for a 16K-token context, which needs a little more memory.

VRAM usage by quantization

445.5 GB

Learn more about VRAM estimation →

Can NVIDIA GeForce RTX 5090 run Mistral Large 3 675B Instruct 2512?

No — Mistral Large 3 675B Instruct 2512 requires at least 204.2 GB at IQ2_XXS, which exceeds the NVIDIA GeForce RTX 5090's 32 GB of VRAM.

What's the best quantization for Mistral Large 3 675B Instruct 2512?

For Mistral Large 3 675B Instruct 2512, Q4_K_M (445.5 GB) offers the best balance of quality and VRAM usage. Q5_K_S (510.5 GB) provides better quality if you have the VRAM. The smallest option is IQ2_XXS at 204.2 GB.

VRAM requirement by quantization

IQ2_XXS
204.2 GB
IQ3_XS
306.3 GB
Q3_K_L
380.5 GB
Q4_K_M ★
445.5 GB
Q5_K_S
510.5 GB
BF16
1485.0 GB

★ Recommended — best balance of quality and VRAM usage.

Learn more about quantization →

Can I run Mistral Large 3 675B Instruct 2512 on a Mac?

Yes — Mac Studio (M3 Ultra, 256GB) and 1 other Mac can run Mistral Large 3 675B Instruct 2512, the smallest at IQ2_S. Apple Silicon uses unified memory, so the model shares RAM with the system. At Q4_K_M you need at least 445.5 GB of usable unified memory (RAM minus macOS overhead), from Mac Studio (M3 Ultra, 512GB).

Can I run Mistral Large 3 675B Instruct 2512 locally?

Yes — Mistral Large 3 675B Instruct 2512 can run locally on consumer hardware. Popular tools include Ollama, LM Studio, and llama.cpp.

What's the download size of Mistral Large 3 675B Instruct 2512?

At Q4_K_M, the download is about 405.00 GB. The full-precision BF16 version is 1350.00 GB. The smallest option (IQ2_XXS) is 185.63 GB.

Which GPUs can run Mistral Large 3 675B Instruct 2512?

No single consumer GPU has enough VRAM to run Mistral Large 3 675B Instruct 2512 at Q4_K_M (445.5 GB). Multi-GPU or professional hardware is required.

Which devices can run Mistral Large 3 675B Instruct 2512?

1 device with unified memory can run Mistral Large 3 675B Instruct 2512 at Q4_K_M (445.5 GB), including Mac Studio (M3 Ultra, 512GB). Apple Silicon Macs use unified memory shared between CPU and GPU, making them well-suited for local LLM inference.